Literature DB >> 23578874

Quantitative genetics: heritability is not always missing.

John F Y Brookfield1.   

Abstract

Quantitative trait loci (QTLs) underlying multifactorial disorders explain little of the heritability - most is 'missing'. A new yeast study has identified QTLs which explain most heritability in traits. Why is heritability missing in human diseases but not here?
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID： 23578874     DOI： 10.1016/j.cub.2013.02.040

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  4 in total

1.  Inferring the Nature of Missing Heritability in Human Traits Using Data from the GWAS Catalog.

Authors:  Eugenio López-Cortegano; Armando Caballero
Journal:  Genetics       Date:  2019-05-13       Impact factor: 4.562

Review 2.  Proteome-Scale Mapping of Perturbed Proteostasis in Living Cells.

Authors:  Isabel Lam; Erinc Hallacli; Vikram Khurana
Journal:  Cold Spring Harb Perspect Biol       Date:  2020-02-03       Impact factor: 10.005

3.  Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students.

Authors:  Bradley T Webb; Alexis C Edwards; Aaron R Wolen; Jessica E Salvatore; Fazil Aliev; Brien P Riley; Cuie Sun; Vernell S Williamson; James N Kitchens; Kimberly Pedersen; Amy Adkins; Megan E Cooke; Jeanne E Savage; Zoe Neale; Seung B Cho; Danielle M Dick; Kenneth S Kendler
Journal:  Front Genet       Date:  2017-03-15       Impact factor: 4.599

4.  Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions.

Authors:  Xuelin Li; Matthew A Price; Dongning He; Anatoli Kamali; Etienne Karita; Shabir Lakhi; Eduard J Sanders; Omu Anzala; Pauli N Amornkul; Susan Allen; Eric Hunter; Richard A Kaslow; Jill Gilmour; Jianming Tang
Journal:  Hum Genet       Date:  2014-06-27       Impact factor: 4.132
  4 in total

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