Literature DB >> 23578867

The ENCODE project: missteps overshadowing a success.

Sean R Eddy1.   

Abstract

Two clichés of science journalism have now played out around the ENCODE project. ENCODE's publicity first presented a misleading "all the textbooks are wrong" narrative about noncoding human DNA. Now several critiques of ENCODE's narrative have been published, and one was so vitriolic that it fueled "undignified academic squabble" stories that focused on tone more than substance. Neither story line does justice to our actual understanding of genomes, to ENCODE's results, or to the role of big science in biology.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID： 23578867     DOI： 10.1016/j.cub.2013.03.023

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  36 in total

1.  The relativity of biological function.

Authors:  Manfred D Laubichler; Peter F Stadler; Sonja J Prohaska; Katja Nowick
Journal:  Theory Biosci       Date:  2015-10-08       Impact factor: 1.919

2.  The Global Invertebrate Genomics Alliance (GIGA): developing community resources to study diverse invertebrate genomes.

Authors:  Heather Bracken-Grissom; Allen G Collins; Timothy Collins; Keith Crandall; Daniel Distel; Casey Dunn; Gonzalo Giribet; Steven Haddock; Nancy Knowlton; Mark Martindale; Mónica Medina; Charles Messing; Stephen J O'Brien; Gustav Paulay; Nicolas Putnam; Timothy Ravasi; Greg W Rouse; Joseph F Ryan; Anja Schulze; Gert Wörheide; Maja Adamska; Xavier Bailly; Jesse Breinholt; William E Browne; M Christina Diaz; Nathaniel Evans; Jean-François Flot; Nicole Fogarty; Matthew Johnston; Bishoy Kamel; Akito Y Kawahara; Tammy Laberge; Dennis Lavrov; François Michonneau; Leonid L Moroz; Todd Oakley; Karen Osborne; Shirley A Pomponi; Adelaide Rhodes; Scott R Santos; Nori Satoh; Robert W Thacker; Yves Van de Peer; Christian R Voolstra; David Mark Welch; Judith Winston; Xin Zhou
Journal:  J Hered       Date:  2014 Jan-Feb       Impact factor: 2.645

Review 3.  Beyond the ENCODE project: using genomics and epigenomics strategies to study enhancer evolution.

Authors:  Noboru Jo Sakabe; Marcelo A Nobrega
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-11-11       Impact factor: 6.237

4.  The way you say it.

Authors: 
Journal:  Nat Methods       Date:  2013-10       Impact factor: 28.547

Review 5.  Comparative population genomics: power and principles for the inference of functionality.

Authors:  David S Lawrie; Dmitri A Petrov
Journal:  Trends Genet       Date:  2014-03-20       Impact factor: 11.639

Review 6.  Eukaryogenesis, how special really?

Authors:  Austin Booth; W Ford Doolittle
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-16       Impact factor: 11.205

7.  Epigenetics: core misconcept.

Authors:  Mark Ptashne
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-12       Impact factor: 11.205

8.  Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance.

Authors: 
Journal:  Mol Cancer Res       Date:  2016-07-11       Impact factor: 5.852

9.  Modular Organization of Cis-regulatory Control Information of Neurotransmitter Pathway Genes in Caenorhabditis elegans.

Authors:  Esther Serrano-Saiz; Burcu Gulez; Laura Pereira; Marie Gendrel; Sze Yen Kerk; Berta Vidal; Weidong Feng; Chen Wang; Paschalis Kratsios; James B Rand; Oliver Hobert
Journal:  Genetics       Date:  2020-05-22       Impact factor: 4.562

10.  Realistic artificial DNA sequences as negative controls for computational genomics.

Authors:  Juan Caballero; Arian F A Smit; Leroy Hood; Gustavo Glusman
Journal:  Nucleic Acids Res       Date:  2014-05-06       Impact factor: 16.971
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