Literature DB >> 23576918

CT scans for pulmonary surveillance may be overused in lower-grade sarcoma.

Benjamin J Miller1, Emily E Carmody Soni, John D Reith, C Parker Gibbs, Mark T Scarborough.   

Abstract

Chest CT scans are often used to monitor patients after excision of a sarcoma. Although sensitive, CT scans are more expensive than chest radiographs and are associated with possible health risks from a higher radiation dose. We hypothesized that a program based upon limited CT scans in lower-grade sarcoma could be efficacious and less expensive. We retrospectively assigned patients to a high-risk or low-risk hypothetical protocol. Eighty-three low- or intermediate-grade soft tissue sarcomas met our inclusion criteria. Eight patients had pulmonary metastasis. A protocol based on selective CT scans for high-risk patients would have identified seven out of eight lesions. The incremental cost-effectiveness ratio for routine CT scans was $731,400. A program based upon selective CT scans for higher-risk patients is accurate, spares unnecessary radiation to many patients, and is less expensive.

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Year:  2012        PMID: 23576918      PMCID: PMC3565411     

Source DB:  PubMed          Journal:  Iowa Orthop J        ISSN: 1541-5457


  36 in total

1.  Indeterminate pulmonary nodules in patients with sarcoma affect survival.

Authors:  Stacy Rissing; Bruce T Rougraff; Kenneth Davis
Journal:  Clin Orthop Relat Res       Date:  2007-06       Impact factor: 4.176

Review 2.  Computed tomography--an increasing source of radiation exposure.

Authors:  David J Brenner; Eric J Hall
Journal:  N Engl J Med       Date:  2007-11-29       Impact factor: 91.245

3.  Prognostic factors in adult patients with locally controlled soft tissue sarcoma. A study of 546 patients from the French Federation of Cancer Centers Sarcoma Group.

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Journal:  J Clin Oncol       Date:  1996-03       Impact factor: 44.544

4.  Utility of chest computed tomography for staging in patients with T1 extremity soft tissue sarcomas.

Authors:  J B Fleming; S B Cantor; D G Varma; D Holst; B W Feig; K K Hunt; S R Patel; R S Benjamin; R E Pollock; P W Pisters
Journal:  Cancer       Date:  2001-08-15       Impact factor: 6.860

5.  Surgical treatment of 297 soft tissue sarcomas of the lower extremity.

Authors:  M H Shiu; E B Castro; S I Hajdu; J G Fortner
Journal:  Ann Surg       Date:  1975-11       Impact factor: 12.969

6.  Localized extremity soft tissue sarcoma: improved knowledge with unchanged survival over time.

Authors:  Jürgen Weitz; Christina R Antonescu; Murray F Brennan
Journal:  J Clin Oncol       Date:  2003-07-15       Impact factor: 44.544

Review 7.  Population screening for lung cancer using computed tomography, is there evidence of clinical effectiveness? A systematic review of the literature.

Authors:  Corri Black; Robyn de Verteuil; Shonagh Walker; Jon Ayres; Angela Boland; Adrian Bagust; Norman Waugh
Journal:  Thorax       Date:  2007-02       Impact factor: 9.139

8.  The significance of pulmonary nodules detected by CT but not by chest radiography in tumour staging.

Authors:  N Chalmers; J J Best
Journal:  Clin Radiol       Date:  1991-12       Impact factor: 2.350

9.  Update on linear non-threshold dose-response model and implications for diagnostic radiology procedures.

Authors:  R Julian Preston
Journal:  Health Phys       Date:  2008-11       Impact factor: 1.316

Review 10.  Radiation risks from exposure to chest computed tomography.

Authors:  Michael V Huppmann; William B Johnson; Marcia C Javitt
Journal:  Semin Ultrasound CT MR       Date:  2010-02       Impact factor: 1.875

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  6 in total

1.  What Is the Clinical Importance of Incidental Findings on Staging CT Scans in Patients With Sarcoma?

Authors:  Zachary Mayo; Sean Kennedy; Yubo Gao; Benjamin J Miller
Journal:  Clin Orthop Relat Res       Date:  2019-04       Impact factor: 4.176

2.  Lung Surveillance Strategy for High-Grade Soft Tissue Sarcomas: Chest X-Ray or CT Scan?

Authors:  Adriana C Gamboa; Cecilia G Ethun; Jeffrey M Switchenko; Joseph Lipscomb; George A Poultsides; Valerie Grignol; J Harrison Howard; T Clark Gamblin; Kevin K Roggin; Konstantinos Votanopoulos; Ryan C Fields; Shishir K Maithel; Keith A Delman; Kenneth Cardona
Journal:  J Am Coll Surg       Date:  2019-08-01       Impact factor: 6.113

3.  Pulmonary Surveillance Strategies Following Sarcoma Excision Vary Among Orthopedic Oncologists: A Survey of the Musculoskeletal Tumor Society.

Authors:  Zachary Ries; C Parker Gibbs; Mark T Scarborough; Benjamin J Miller
Journal:  Iowa Orthop J       Date:  2016

4.  Developing an Evidence-based Followup Schedule for Bone Sarcomas Based on Local Recurrence and Metastatic Progression.

Authors:  Cara Cipriano; Anthony M Griffin; Peter C Ferguson; Jay S Wunder
Journal:  Clin Orthop Relat Res       Date:  2017-03       Impact factor: 4.176

5.  Surveillance Strategies for Sarcoma: Results of a Survey of Members of the Musculoskeletal Tumor Society.

Authors:  David D Greenberg; Brooke Crawford
Journal:  Sarcoma       Date:  2016-07-13

Review 6.  Multidisciplinary management of soft tissue sarcoma.

Authors:  Lukas M Nystrom; Nickolas B Reimer; John D Reith; Long Dang; Robert A Zlotecki; Mark T Scarborough; C Parker Gibbs
Journal:  ScientificWorldJournal       Date:  2013-07-28
  6 in total

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