Literature DB >> 23576430

A silicon photonic biosensor using phase-shifted Bragg gratings in slot waveguide.

Xu Wang1, Jonas Flueckiger, Shon Schmidt, Samantha Grist, Sahba T Fard, James Kirk, Matt Doerfler, Karen C Cheung, Daniel M Ratner, Lukas Chrostowski.   

Abstract

We present a novel silicon photonic biosensor using phase-shifted Bragg gratings in a slot waveguide. The optical field is concentrated inside the slot region, leading to efficient light-matter interaction. The Bragg gratings are formed with sidewall corrugations on the outside of the waveguide, and a phase shift is introduced to create a sharp resonant peak within the stop band. We experimentally demonstrate a high sensitivity of 340 nm/RIU measured in salt solutions and a high quality factor of 1.5 × 10⁴, enabling a low intrinsic limit of detection of 3 × 10⁻⁴ RIU. Furthermore, the silicon device was fabricated by a CMOS foundry, facilitating high-volume and low-cost production. Finally, we demonstrate the device's ability to interrogate specific biomolecular interactions, resulting in the first of its kind label-free biosensor.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Bragg grating; biosensor; limit of detection; microfluidics; silicon photonics; slot waveguide

Mesh:

Substances:

Year:  2013        PMID: 23576430     DOI: 10.1002/jbio.201300012

Source DB:  PubMed          Journal:  J Biophotonics        ISSN: 1864-063X            Impact factor:   3.207


  9 in total

1.  Sensitivity Improvement of Multi-Slot Subwavelength Bragg Grating Refractive Index Sensors by Increasing the Waveguide Height or Suspending the Sensor.

Authors:  Siim Heinsalu; Katsuyuki Utaka
Journal:  Sensors (Basel)       Date:  2022-05-29       Impact factor: 3.847

2.  Slot-Waveguide Silicon Nitride Organic Hybrid Distributed Feedback Laser.

Authors:  Florian Vogelbacher; Martin Sagmeister; Jochen Kraft; Xue Zhou; Jinhua Huang; Mingzhu Li; Ke-Jian Jiang; Yanlin Song; Karl Unterrainer; Rainer Hainberger
Journal:  Sci Rep       Date:  2019-12-05       Impact factor: 4.379

3.  Critical assessment of relevant methods in the field of biosensors with direct optical detection based on fibers and waveguides using plasmonic, resonance, and interference effects.

Authors:  Günter Gauglitz
Journal:  Anal Bioanal Chem       Date:  2020-04-20       Impact factor: 4.142

4.  Numerical Simulation of Optical Sensing by the Far Field Pattern Radiated by Periodic Grating Strips Over Silica Buffer on the Silicon Wire Waveguide.

Authors:  Andrei Tsarev; Vittorio M N Passaro
Journal:  Sensors (Basel)       Date:  2020-09-16       Impact factor: 3.576

5.  Optimization of Silicon Nitride Waveguide Platform for On-Chip Virus Detection.

Authors:  Raghi S El Shamy; Mohamed A Swillam; Xun Li
Journal:  Sensors (Basel)       Date:  2022-02-02       Impact factor: 3.576

6.  Numerical Optimization of a Nanophotonic Cavity by Machine Learning for Near-Unity Photon Indistinguishability at Room Temperature.

Authors:  J Guimbao; L Sanchis; L Weituschat; J Manuel Llorens; M Song; J Cardenas; P Aitor Postigo
Journal:  ACS Photonics       Date:  2022-05-11       Impact factor: 7.077

7.  A fully reconfigurable waveguide Bragg grating for programmable photonic signal processing.

Authors:  Weifeng Zhang; Jianping Yao
Journal:  Nat Commun       Date:  2018-04-11       Impact factor: 14.919

8.  Wavelength-Flattened Directional Coupler Based Mid-Infrared Chemical Sensor Using Bragg Wavelength in Subwavelength Grating Structure.

Authors:  Bowei Dong; Ting Hu; Xianshu Luo; Yuhua Chang; Xin Guo; Hong Wang; Dim-Lee Kwong; Guo-Qiang Lo; Chengkuo Lee
Journal:  Nanomaterials (Basel)       Date:  2018-11-01       Impact factor: 5.076

Review 9.  Silicon Photonic Biosensors Using Label-Free Detection.

Authors:  Enxiao Luan; Hossam Shoman; Daniel M Ratner; Karen C Cheung; Lukas Chrostowski
Journal:  Sensors (Basel)       Date:  2018-10-18       Impact factor: 3.576

  9 in total

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