Literature DB >> 23575266

IBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CA.

Peter-Christian Klöhn1, Ulrich Wuellner, Nora Zizlsperger, Yu Zhou, Daniel Tavares, Sven Berger, Kirstin A Zettlitz, Gabriele Proetzel, May Yong, Richard H J Begent, Janice M Reichert.   

Abstract

The 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences, and the 2012 Annual Meeting of The Antibody Society, organized by IBC Life Sciences with contributions from The Antibody Society and two Scientific Advisory Boards, were held December 3-6, 2012 in San Diego, CA. The meeting drew over 800 participants who attended sessions on a wide variety of topics relevant to antibody research and development. As a prelude to the main events, a pre-conference workshop held on December 2, 2012 focused on intellectual property issues that impact antibody engineering. The Antibody Engineering Conference was composed of six sessions held December 3-5, 2012: (1) From Receptor Biology to Therapy; (2) Antibodies in a Complex Environment; (3) Antibody Targeted CNS Therapy: Beyond the Blood Brain Barrier; (4) Deep Sequencing in B Cell Biology and Antibody Libraries; (5) Systems Medicine in the Development of Antibody Therapies/Systematic Validation of Novel Antibody Targets; and (6) Antibody Activity and Animal Models. The Antibody Therapeutics conference comprised four sessions held December 4-5, 2012: (1) Clinical and Preclinical Updates of Antibody-Drug Conjugates; (2) Multifunctional Antibodies and Antibody Combinations: Clinical Focus; (3) Development Status of Immunomodulatory Therapeutic Antibodies; and (4) Modulating the Half-Life of Antibody Therapeutics. The Antibody Society's special session on applications for recording and sharing data based on GIATE was held on December 5, 2012, and the conferences concluded with two combined sessions on December 5-6, 2012: (1) Development Status of Early Stage Therapeutic Antibodies; and (2) Immunomodulatory Antibodies for Cancer Therapy.

Entities:  

Keywords:  antibody engineering; antibody therapeutics; antibody-drug conjugates; bispecific antibodies; computational design

Mesh:

Substances:

Year:  2013        PMID: 23575266      PMCID: PMC3893229          DOI: 10.4161/mabs.23655

Source DB:  PubMed          Journal:  MAbs        ISSN: 1942-0862            Impact factor:   5.857


  86 in total

1.  Dual-targeting immunotherapy of lymphoma: potent cytotoxicity of anti-CD20/CD74 bispecific antibodies in mantle cell and other lymphomas.

Authors:  Pankaj Gupta; David M Goldenberg; Edmund A Rossi; Thomas M Cardillo; John C Byrd; Natarajan Muthusamy; Richard R Furman; Chien-Hsing Chang
Journal:  Blood       Date:  2012-01-23       Impact factor: 22.113

2.  Data standards for minimum information collection for antibody therapy experiments.

Authors:  M Yong; B Tolner; S Nagl; R B Pedley; K Chester; A J Green; A Mayer; S Sharma; R Begent
Journal:  Protein Eng Des Sel       Date:  2009-03       Impact factor: 1.650

3.  Consistent manufacturing and quality control of a highly complex recombinant polyclonal antibody product for human therapeutic use.

Authors:  Torben P Frandsen; Henrik Naested; Søren K Rasmussen; Peter Hauptig; Finn C Wiberg; Lone Kjaer Rasmussen; Anne Marie Valentin Jensen; Pia Persson; Margareta Wikén; Anders Engström; Yun Jiang; Susan J Thorpe; Cecilia Förberg; Anne B Tolstrup
Journal:  Biotechnol Bioeng       Date:  2011-04-25       Impact factor: 4.530

4.  Generation of stable cell clones expressing mixtures of human antibodies.

Authors:  John de Kruif; Arjen Kramer; Roy Nijhuis; Vanessa van der Zande; Renate den Blanken; Carina Clements; Therèse Visser; Rob Keehnen; Marcel den Hartog; Mark Throsby; Ton Logtenberg
Journal:  Biotechnol Bioeng       Date:  2010-08-01       Impact factor: 4.530

Review 5.  Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier.

Authors:  William M Pardridge; Ruben J Boado
Journal:  Methods Enzymol       Date:  2012       Impact factor: 1.600

6.  Receptor-mediated abeta amyloid antibody targeting to Alzheimer's disease mouse brain.

Authors:  Qing-Hui Zhou; Ailing Fu; Ruben J Boado; Eric Ka-Wai Hui; Jeff Zhiqiang Lu; William M Pardridge
Journal:  Mol Pharm       Date:  2010-12-21       Impact factor: 4.939

7.  Passive immunization against pyroglutamate-3 amyloid-β reduces plaque burden in Alzheimer-like transgenic mice: a pilot study.

Authors:  Jeffrey L Frost; Bin Liu; Martin Kleinschmidt; Stephan Schilling; Hans-Ulrich Demuth; Cynthia A Lemere
Journal:  Neurodegener Dis       Date:  2012-02-16       Impact factor: 2.977

8.  Broad neutralization coverage of HIV by multiple highly potent antibodies.

Authors:  Laura M Walker; Michael Huber; Katie J Doores; Emilia Falkowska; Robert Pejchal; Jean-Philippe Julien; Sheng-Kai Wang; Alejandra Ramos; Po-Ying Chan-Hui; Matthew Moyle; Jennifer L Mitcham; Phillip W Hammond; Ole A Olsen; Pham Phung; Steven Fling; Chi-Huey Wong; Sanjay Phogat; Terri Wrin; Melissa D Simek; Wayne C Koff; Ian A Wilson; Dennis R Burton; Pascal Poignard
Journal:  Nature       Date:  2011-09-22       Impact factor: 49.962

9.  Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis.

Authors:  Eveline Trachsel; Frank Bootz; Michela Silacci; Manuela Kaspar; Hartwig Kosmehl; Dario Neri
Journal:  Arthritis Res Ther       Date:  2007       Impact factor: 5.156

10.  Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys.

Authors:  Philip R Johnson; Bruce C Schnepp; Jianchao Zhang; Mary J Connell; Sean M Greene; Eloisa Yuste; Ronald C Desrosiers; K Reed Clark
Journal:  Nat Med       Date:  2009-05-17       Impact factor: 53.440

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  3 in total

Review 1.  Enhancing Cancer Immunotherapy Via Activation of Innate Immunity.

Authors:  Jacob L Goldberg; Paul M Sondel
Journal:  Semin Oncol       Date:  2015-06-03       Impact factor: 4.929

Review 2.  Immunoglobulin Fc Heterodimer Platform Technology: From Design to Applications in Therapeutic Antibodies and Proteins.

Authors:  Ji-Hee Ha; Jung-Eun Kim; Yong-Sung Kim
Journal:  Front Immunol       Date:  2016-10-06       Impact factor: 7.561

3.  Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody.

Authors:  Natalia Ponomarenko; Spyros D Chatziefthimiou; Inna Kurkova; Yuliana Mokrushina; Yuliana Mokrushina; Anastasiya Stepanova; Ivan Smirnov; Marat Avakyan; Tatyana Bobik; Azad Mamedov; Vladimir Mitkevich; Alexey Belogurov; Olga S Fedorova; Michael Dubina; Andrey Golovin; Victor Lamzin; Alain Friboulet; Alexander A Makarov; Matthias Wilmanns; Alexander Gabibov
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2014-02-15
  3 in total

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