Literature DB >> 23573959

[Ir(P-OP)]-catalyzed asymmetric hydrogenation of diversely substituted C═N-containing heterocycles.

José Luis Núñez-Rico1, Anton Vidal-Ferran.   

Abstract

Iridium(I) complexes of enantiomerically pure phosphine-phosphite ligands ([Ir(Cl)(cod)(P-OP)]) efficiently catalyze the enantioselective hydrogenation of diverse C═N-containing heterocyclic compounds (benzoxazines, benzoxazinones, benzothiazinones, and quinoxalinones; 25 examples, up to 99% ee). A substrate-to-catalyst ratio as high as 2000:1 was reached.

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Year:  2013        PMID： 23573959     DOI： 10.1021/ol400854a

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  Carbene-Catalyzed Enantioselective Decarboxylative Annulations to Access Dihydrobenzoxazinones and Quinolones.

Authors:  Ansoo Lee; Joshua L Zhu; Taisiia Feoktistova; Alexander C Brueckner; Paul H-Y Cheong; Karl A Scheidt
Journal:  Angew Chem Int Ed Engl       Date:  2019-03-27       Impact factor: 15.336

2.  Application of Silver Nanoparticles in the Multicomponent Reaction Domain: A Combined Catalytic Reduction Methodology to Efficiently Access Potential Hypertension or Inflammation Inhibitors.

Authors:  Domna Iordanidou; Tryfon Zarganes-Tzitzikas; Constantinos G Neochoritis; Alexander Dömling; Ioannis N Lykakis
Journal:  ACS Omega       Date:  2018-11-27

3.  Ni-catalyzed asymmetric hydrogenation of N-aryl imino esters for the efficient synthesis of chiral α-aryl glycines.

Authors:  Dan Liu; Bowen Li; Jianzhong Chen; Ilya D Gridnev; Deyue Yan; Wanbin Zhang
Journal:  Nat Commun       Date:  2020-11-23       Impact factor: 14.919

4.  Asymmetric hydrogenation for the synthesis of 2-substituted chiral morpholines.

Authors:  Mingxu Li; Jian Zhang; Yashi Zou; Fengfan Zhou; Zhenfeng Zhang; Wanbin Zhang
Journal:  Chem Sci       Date:  2021-10-28       Impact factor: 9.825

5.  Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones.

Authors:  Domna Iordanidou; Michael G Kallitsakis; Marina A Tzani; Dimitris I Ioannou; Tryfon Zarganes-Tzitzikas; Constantinos G Neochoritis; Alexander Dömling; Michael A Terzidis; Ioannis N Lykakis
Journal:  Molecules       Date:  2022-07-08       Impact factor: 4.927

6.  Chemoenzymatic Asymmetric Synthesis of Complex Heterocycles: Dihydrobenzoxazinones and Dihydroquinoxalinones.

Authors:  Mohammad Faizan Bhat; Alejandro Prats Luján; Mohammad Saifuddin; Gerrit J Poelarends
Journal:  ACS Catal       Date:  2022-09-06       Impact factor: 13.700

7.  Highly efficient Ir-catalyzed asymmetric hydrogenation of benzoxazinones and derivatives with a Brønsted acid cocatalyst.

Authors:  Zhengyu Han; Gang Liu; Rui Wang; Xiu-Qin Dong; Xumu Zhang
Journal:  Chem Sci       Date:  2019-03-19       Impact factor: 9.825
  7 in total

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