PURPOSE: To characterize in vivo microscopic features of healthy oral mucosa by noninvasive, real-time reflectance confocal microscopy (RCM). MATERIAL AND METHODS: One hundred healthy mucosal sites (38 lips, 24 cheeks, 10 gingivae, and 28 tongues) from 50 randomly selected volunteers were imaged by a commercially available in vivo RCM (Vivascope3000, Lucid, Rochester, NY). Morphological results were described and correlated with conventional histology. RESULTS: Specific microscopic parameters (cellular morphology, anatomical structures features, architectural patterns) were identified by RCM for each mucosal site. CONCLUSIONS: RCM features reproducibility in different mucosal sites and subjects, which suggests that RCM can be an adjunct tool for clinical management in stomatology.
PURPOSE: To characterize in vivo microscopic features of healthy oral mucosa by noninvasive, real-time reflectance confocal microscopy (RCM). MATERIAL AND METHODS: One hundred healthy mucosal sites (38 lips, 24 cheeks, 10 gingivae, and 28 tongues) from 50 randomly selected volunteers were imaged by a commercially available in vivo RCM (Vivascope3000, Lucid, Rochester, NY). Morphological results were described and correlated with conventional histology. RESULTS: Specific microscopic parameters (cellular morphology, anatomical structures features, architectural patterns) were identified by RCM for each mucosal site. CONCLUSIONS: RCM features reproducibility in different mucosal sites and subjects, which suggests that RCM can be an adjunct tool for clinical management in stomatology.
Authors: Pablo Uribe; Helena Collgros; Richard A Scolyer; Scott W Menzies; Pascale Guitera Journal: JAMA Dermatol Date: 2017-09-01 Impact factor: 10.282
Authors: Cory Olsovsky; Taylor Hinsdale; Rodrigo Cuenca; Yi-Shing Lisa Cheng; John M Wright; Terry D Rees; Javier A Jo; Kristen C Maitland Journal: J Biomed Opt Date: 2017-05-01 Impact factor: 3.170