Synthesis and screening of analgesic and anti-inflammatory activity of 6-acyl-3-(4-substituted benzoylmethyl)-2(3H)-benzoxazolones.

In this study, the synthesis and analgesic and anti-inflammatory activities of some new 6-acyl-3-(4-substituted benzoylmethyl)-2(3H)-benzoxazolone derivatives are reported. Their structures were confirmed by microanalysis, IR and NMR spectral analysis. Their analgesic activities were determined by using modified Koster method, and antiinflammatory activities were determined by using Peacock Dial Thickness Gauge Ozaki.