Kai J Buhling1, Donata Grajecki. 1. Clinic for Gynecology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. k.buehling@uke.de
Abstract
PURPOSE OF REVIEW: Benefit of micronutrient supplementation on female fertility. RECENT FINDINGS: Reports of randomized trials are rare. Most studies are focused on multivitamin supplementations. For some micronutrients, a positive impact on fertility could be shown. This article reviews the available clinical studies as well as the pathophysiological background of possible effects and summarizes the potential benefits of selected micronutrients on female fertility. SUMMARY: Apart from lowering the malformation risk by periconceptional supplementation of folic acid, substitution with different micronutrients, particularly folic acid, vitamin B6, vitamin C, vitamin D, vitamin E, iodine, selenium, iron, and DHA might have a positive impact on infertility treatment. The multivitamin formulation should take the pathophysiology, clinical studies, and upper limits into account.
PURPOSE OF REVIEW: Benefit of micronutrient supplementation on female fertility. RECENT FINDINGS: Reports of randomized trials are rare. Most studies are focused on multivitamin supplementations. For some micronutrients, a positive impact on fertility could be shown. This article reviews the available clinical studies as well as the pathophysiological background of possible effects and summarizes the potential benefits of selected micronutrients on female fertility. SUMMARY: Apart from lowering the malformation risk by periconceptional supplementation of folic acid, substitution with different micronutrients, particularly folic acid, vitamin B6, vitamin C, vitamin D, vitamin E, iodine, selenium, iron, and DHA might have a positive impact on infertility treatment. The multivitamin formulation should take the pathophysiology, clinical studies, and upper limits into account.
Authors: Kristin Palmsten; Katrina F Flores; Christina D Chambers; Lauren A Weiss; Rajeshwari Sundaram; Germaine M Buck Louis Journal: Reprod Sci Date: 2017-04-12 Impact factor: 3.060
Authors: Muhammad Abu-Elmagd; Mourad Assidi; Hans-Juergen Schulten; Ashraf Dallol; Peter Pushparaj; Farid Ahmed; Stephen W Scherer; Mohammed Al-Qahtani Journal: BMC Med Genomics Date: 2015-01-15 Impact factor: 3.063