| Literature DB >> 23571637 |
Aurore Fraix1, Noufal Kandoth, Ilse Manet, Venera Cardile, Adriana C E Graziano, Ruxandra Gref, Salvatore Sortino.
Abstract
A multifunctional nanoplatform with four-in-one photoresponsive functionalities has been achieved through the co-encapsulation of two chromo-fluorogenic components within biocompatible polymeric nanoparticles. This engineered nanoconstruct efficiently delivers different photosensitizers in melanoma cells, which can be detected through their dual-color fluorescence, and induces amplified cell mortality due to the simultaneous photogeneration of singlet oxygen and nitric oxide.Entities:
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Year: 2013 PMID: 23571637 DOI: 10.1039/c3cc40714d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222