| Literature DB >> 2357153 |
S J Huber1, D W Chakeres, G W Paulson, R Khanna.
Abstract
Magnetic resonance imaging was utilized to examine changes in the pars compacta associated with Parkinson's disease. We found a reduction in average width of the pars compacta in advanced- but not early-stage patients. Conversely, a significant difference in width (right minus left) was observed in early- but not late-stage patients. Width asymmetry may be a sensitive magnetic resonance imaging indicator for the early detection of Parkinson's disease when there is a predominance of unilateral clinical symptoms.Entities:
Mesh:
Year: 1990 PMID: 2357153 DOI: 10.1001/archneur.1990.00530070023006
Source DB: PubMed Journal: Arch Neurol ISSN: 0003-9942