OBJECTIVE: To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris (G. vulgaris) Nees. METHODS: G. vulgaris Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala.Various parts of this plant have been used in the treatment of ulcers, sores, inflammation, dyspepsia, healing of wounds, etc. The present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation (HRBC) method and in vivo method was estimated on the carrageenan induced paw oedima. RESULTS: Both the methods showed significant anti-inflammatory property of the different extracts tested. CONCLUSIONS: The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium.
OBJECTIVE: To evaluate the anti-inflammatory property of the leaf exacts of Gendarussa vulgaris (G. vulgaris) Nees. METHODS:G. vulgaris Nees of the family Apocynaceae is a medium sized tree grown in semishade or no shade and is common in the Ernad and Nilambur taluks of Kerala.Various parts of this plant have been used in the treatment of ulcers, sores, inflammation, dyspepsia, healing of wounds, etc. The present study aimed at the evaluation of anti-inflammatory property of the aqueous and alcoholic extracts of the leaves by both in vitro and in vivo methods. In vitro method was estimated by human red blood cell membrane stabilisation (HRBC) method and in vivo method was estimated on the carrageenan induced paw oedima. RESULTS: Both the methods showed significant anti-inflammatory property of the different extracts tested. CONCLUSIONS: The alcoholic extract at a concentration of 300 mg/mL showed potent activity on comparing with the standard drug diclofenac sodium.
Authors: Shafiqul Islam; Fowzul Islam Fahad; Arifa Sultana; Syed Al Jawad Sayem; Shawon Baran Roy; Mohammad Nazmul Islam; Arpita Roy; Mohammed Abu Sayeed Journal: Evid Based Complement Alternat Med Date: 2022-02-15 Impact factor: 2.629
Authors: Protus Arrey Tarkang; Faith A Okalebo; Juma D Siminyu; William N Ngugi; Amos M Mwaura; Jackson Mugweru; Gabriel A Agbor; Anastasia N Guantai Journal: BMC Complement Altern Med Date: 2015-06-09 Impact factor: 3.659
Authors: Yousra Shafiq; Syed Baqir Shyum Naqvi; Ghazala H Rizwani; Muhammad Arif Asghar; Rabia Bushra; Sana Ghayas; Ahad Abdul Rehman; Muhammad Asif Asghar Journal: BMC Complement Med Ther Date: 2021-05-01