| Literature DB >> 2356850 |
J A Tumlin1, J M Sands, A Someren.
Abstract
The authors present a patient who experienced cocaine-related thrombotic microangiopathy and patchy renal cortical necrosis, associated with the clinical syndrome of microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure, characteristics of the Hemolytic-Uremic syndrome. The proposed pathogenetic mechanisms include: (1) cocaine-induced vasoconstriction and endothelial damage and (2) procoagulant effects of cocaine.Entities:
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Year: 1990 PMID: 2356850 DOI: 10.1097/00000441-199006000-00002
Source DB: PubMed Journal: Am J Med Sci ISSN: 0002-9629 Impact factor: 2.378