| Literature DB >> 23567962 |
Juan C Cedrón1, David Gutiérrez, Ninoska Flores, Ángel G Ravelo, Ana Estévez-Braun.
Abstract
A set of twenty one lycorenine derivatives has been prepared from the alkaloid hippeastrine (1). The modifications performed on hippeastrine included some functional group transformations, structural simplification and preparation of dimers. All alkaloids were tested as potential antimalarial agents, being the hippeastrine dimers the most active compounds.Entities:
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Year: 2013 PMID： 23567962 DOI： 10.1016/j.ejmech.2013.03.018
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514