Literature DB >> 23567872

Molecular recognition of sulfotyrosine and phosphotyrosine by the Src homology 2 domain.

Tong Ju1, Wei Niu, Ronald Cerny, Joshua Bollman, Anthony Roy, Jiantao Guo.   

Abstract

We study molecular recognition of two closely resembling posttranslational modification products, phosphotyrosine (pTyr) and sulfotyrosine (sTyr). The differences in charge, size, and binding geometry of pTyr and sTyr are the main recognition elements. Protein engineering can be applied to alter the specificity and strength of the recognition.

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Year:  2013        PMID： 23567872     DOI： 10.1039/c3mb70061e

Source DB:  PubMed          Journal:  Mol Biosyst        ISSN： 1742-2051


  7 in total

Review 1.  Emerging patterns of tyrosine sulfation and O-glycosylation cross-talk and co-localization.

Authors:  Akul Y Mehta; Jamie Heimburg-Molinaro; Richard D Cummings; Christoffer K Goth
Journal:  Curr Opin Struct Biol       Date:  2020-01-09       Impact factor: 6.809

2.  Sulfotyrosine dipeptide: Synthesis and evaluation as HIV-entry inhibitor.

Authors:  Tong Ju; Duoyi Hu; Shi-Hua Xiang; Jiantao Guo
Journal:  Bioorg Chem       Date:  2016-07-25       Impact factor: 5.275

3.  Fine-tuning interaction between aminoacyl-tRNA synthetase and tRNA for efficient synthesis of proteins containing unnatural amino acids.

Authors:  Nanxi Wang; Tong Ju; Wei Niu; Jiantao Guo
Journal:  ACS Synth Biol       Date:  2014-05-23       Impact factor: 5.110

4.  CCR7 Sulfotyrosine Enhances CCL21 Binding.

Authors:  Andrew J Phillips; Deni Taleski; Chad A Koplinski; Anthony E Getschman; Natasha A Moussouras; Amanda M Richard; Francis C Peterson; Michael B Dwinell; Brian F Volkman; Richard J Payne; Christopher T Veldkamp
Journal:  Int J Mol Sci       Date:  2017-08-25       Impact factor: 5.923

5.  A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.

Authors:  Martin Kulke; Felix Nagel; Lukas Schulig; Norman Geist; Marcel Gabor; Julia Mayerle; Markus M Lerch; Andreas Link; Mihaela Delcea
Journal:  J Inflamm Res       Date:  2021-05-21

6.  Engineering of a Small Protein Scaffold To Recognize Sulfotyrosine with High Specificity.

Authors:  Justin Lawrie; Sean Waldrop; Anya Morozov; Wei Niu; Jiantao Guo
Journal:  ACS Chem Biol       Date:  2021-07-12       Impact factor: 4.634

7.  Functional genetic encoding of sulfotyrosine in mammalian cells.

Authors:  Xinyuan He; Yan Chen; Daisy Guiza Beltran; Maia Kelly; Bin Ma; Justin Lawrie; Feng Wang; Eric Dodds; Limei Zhang; Jiantao Guo; Wei Niu
Journal:  Nat Commun       Date:  2020-09-24       Impact factor: 14.919
  7 in total

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