Literature DB >> 23566738

Changes in bone mineral density of the distal femur after total knee arthroplasty: a 7-year DEXA follow-up comparing results between obese and nonobese patients.

Jaakko Järvenpää1, Tarja Soininvaara2, Jukka Kettunen3, Hannu Miettinen3, Heikki Kröger4.   

Abstract

BACKGROUND AND
PURPOSE: Periprosthetic femoral bone mineral density (BMD, g/cm2) decreases after total knee arthroplasty (TKA) as a result of the stress-shielding phenomenon. It is not known whether obesity has an effect on this phenomenon or not. The aim of this study was to assess long-term periprosthetic BMD changes after TKA and compare whether there is a difference between obese and nonobese patients.
METHODS: A total of 69 TKAs in 61 patients were performed, and BMD measurements of the distal femur were followed up to 7 years postoperatively. The patients were divided into two study groups according to their body mass index, and the groups were compared in relation to BMD and functional outcome.
RESULTS: The mean of periprosthetic bone loss during the 7-year follow-up varied from 10.3% to 30.6% depending on the region of interest (p<0.0005). The highest bone-loss rates were detected during the first three postoperative months. A total of 26 patients were categorized as obese with a body mass index value of ≥30 kg/m2. The obese patients' total periprosthetic BMD was higher at both baseline (8.6%) and 7 years after operation (p=0.05) (15.2%).
CONCLUSION: Periprosthetic bone loss around the femoral component continued for up to 7 years postoperatively. The loss of bone density was not associated with any negative clinical outcome in this study, but periprosthetic bone loss was of a smaller quantity in the obese which is probably due to higher weight induced stresses on bone.
Copyright © 2013 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  BMD; Obesity; Stress shielding; TKA

Mesh:

Year:  2013        PMID: 23566738     DOI: 10.1016/j.knee.2013.03.004

Source DB:  PubMed          Journal:  Knee        ISSN: 0968-0160            Impact factor:   2.199


  14 in total

1.  Changes in the three-dimensional load-bearing axis after mobile-bearing total knee arthroplasty.

Authors:  Yoshinori Ishii; Hideo Noguchi; Junko Sato; Nobukazu Ezawa; Shin-Ichi Toyabe
Journal:  Eur J Orthop Surg Traumatol       Date:  2016-04-21

2.  [Progress of change in bone mineral density after knee arthroplasty].

Authors:  Wenxing Wei; Yuangang Wu; Yi Zeng; Bin Shen
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2021-01-15

3.  Modulation and predictors of periprosthetic bone mineral density following total knee arthroplasty.

Authors:  Anett Mau-Moeller; Martin Behrens; Sabine Felser; Sven Bruhn; Wolfram Mittelmeier; Rainer Bader; Ralf Skripitz
Journal:  Biomed Res Int       Date:  2015-02-08       Impact factor: 3.411

4.  A preclinical numerical assessment of a polyetheretherketone femoral component in total knee arthroplasty during gait.

Authors:  Lennert de Ruiter; Dennis Janssen; Adam Briscoe; Nico Verdonschot
Journal:  J Exp Orthop       Date:  2017-02-01

5.  Preoperative Periarticular Knee Bone Mineral Density in Osteoarthritic Patients Undergoing TKA.

Authors:  Yoshinori Ishii; Hideo Noguchi; Junko Sato; Koji Todoroki; Nobukazu Ezawa; Shin-Ichi Toyabe
Journal:  Open Orthop J       Date:  2016-08-19

6.  Do patients lose weight after total knee replacement?

Authors:  Carlos Roberto Schwartsmann; Alexandre Moreira Borges; Geraldo Luiz Schuck de Freitas; Eduardo Zaniol Migon; Gustavo Kaempf de Oliveira; Marcos Wainberg Rodrigues
Journal:  Rev Bras Ortop       Date:  2017-01-24

7.  Effect of bisphosphonates on periprosthetic bone loss after total knee arthroplasty: a meta-analysis of randomized controlled trials.

Authors:  Mingmin Shi; Lei Chen; Haobo Wu; Yangxin Wang; Wei Wang; Yujie Zhang; Shigui Yan
Journal:  BMC Musculoskelet Disord       Date:  2018-05-30       Impact factor: 2.362

8.  Densitometric evaluation might prevent failure of knee artroplasty for aseptic loosening. An 8-year observational controlled study.

Authors:  Gianantonio Saviola; Irene Zaghini; Lul Abdi-Ali; Gregorio Ferlini; Silvano Sacco; Maurizio Rossini
Journal:  Saudi Med J       Date:  2016-02       Impact factor: 1.484

9.  Does a PEEK Femoral TKA Implant Preserve Intact Femoral Surface Strains Compared With CoCr? A Preliminary Laboratory Study.

Authors:  Kathryn E Rankin; Alexander S Dickinson; Adam Briscoe; Martin Browne
Journal:  Clin Orthop Relat Res       Date:  2016-11       Impact factor: 4.176

10.  The mechanical response of a polyetheretherketone femoral knee implant under a deep squatting loading condition.

Authors:  Lennert de Ruiter; Dennis Janssen; Adam Briscoe; Nico Verdonschot
Journal:  Proc Inst Mech Eng H       Date:  2017-11-04       Impact factor: 1.617

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.