| Literature DB >> 23565818 |
Nobuyuki Mase1, Takuya Horibe.
Abstract
The Knoevenagel condensation between an active methylene compound and an aromatic aldehyde with a carbamic acid ammonium salt used as an organocatalyst gave the desired Knoevenagel products in up to 98% yield. The reaction occurred at rt and in a short reaction time under solvent-free conditions. In addition, no extraction, wash, or chromatography steps were needed to obtain a high-purity Knoevenagel product.Entities:
Year: 2013 PMID： 23565818 DOI： 10.1021/ol400462d
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005