Xiaoyan Wang1, Juan Qin, Lifang Wang, Jinyun Chen, Wenzhi Chen, Liangdan Tang. 1. Department of Obstetrics and Gynecology, First Affiliated Hospital, Chongqing Medical University, 1 Yi Xue Yuan Road, Yu Zhong District, Chongqing, 400016, People's Republic of China.
Abstract
BACKGROUND:Uterine fibroids are the most common benign tumors in women. As a new minimally invasive clinical technology, high-intensity focused ultrasound (HIFU) has been widely applied to the treatment of uterine fibroids, but no study using objective criteria has evaluated the effect of HIFU on sexual function. METHODS: A total of 100 premenopausal patients were enrolled in this randomized clinical trial (RCT). The brief index of sexual functioning (BISF-W) was used to evaluate changes in sexual function. Differences in the outcome were calculated for each individual before treatment and at 3 and 6 months after treatment, and changes were compared between the HIFU group (HIFUG) and the myomectomy group (MYG). RESULTS:Preoperative BISF-W scores were similar in both groups (P < 0.05). No significant differences were found between the two groups at 3 and 6 month after treatment. Within the groups, patients reported less arousal and less problems at 3 month compared to baseline. There was a trend toward improved sexual satisfaction and overall quality of sexual life in both groups 6 months after treatment compared with the baseline, although it failed to reach statistical significance except for the dimensions of relational satisfaction and problems affecting sexuality. CONCLUSIONS:Sexual function improved on average to some degree after both HIFU and conventional myomectomy.
RCT Entities:
BACKGROUND: Uterine fibroids are the most common benign tumors in women. As a new minimally invasive clinical technology, high-intensity focused ultrasound (HIFU) has been widely applied to the treatment of uterine fibroids, but no study using objective criteria has evaluated the effect of HIFU on sexual function. METHODS: A total of 100 premenopausal patients were enrolled in this randomized clinical trial (RCT). The brief index of sexual functioning (BISF-W) was used to evaluate changes in sexual function. Differences in the outcome were calculated for each individual before treatment and at 3 and 6 months after treatment, and changes were compared between the HIFU group (HIFUG) and the myomectomy group (MYG). RESULTS: Preoperative BISF-W scores were similar in both groups (P < 0.05). No significant differences were found between the two groups at 3 and 6 month after treatment. Within the groups, patients reported less arousal and less problems at 3 month compared to baseline. There was a trend toward improved sexual satisfaction and overall quality of sexual life in both groups 6 months after treatment compared with the baseline, although it failed to reach statistical significance except for the dimensions of relational satisfaction and problems affecting sexuality. CONCLUSIONS: Sexual function improved on average to some degree after both HIFU and conventional myomectomy.
Authors: Emily P Barnard; Ahmed M AbdElmagied; Lisa E Vaughan; Amy L Weaver; Shannon K Laughlin-Tommaso; Gina K Hesley; David A Woodrum; Vanessa L Jacoby; Maureen P Kohi; Thomas M Price; Angel Nieves; Michael J Miller; Bijan J Borah; Krzysztof R Gorny; Phyllis C Leppert; Lisa G Peterson; Elizabeth A Stewart Journal: Am J Obstet Gynecol Date: 2017-01-05 Impact factor: 8.661
Authors: Ahmed M AbdElmagied; Lisa E Vaughan; Amy L Weaver; Shannon K Laughlin-Tommaso; Gina K Hesley; David A Woodrum; Vanessa L Jacoby; Maureen P Kohi; Thomas M Price; Angel Nieves; Michael J Miller; Bijan J Borah; Krzysztof R Gorny; Phyllis C Leppert; Maureen A Lemens; Elizabeth A Stewart Journal: Am J Obstet Gynecol Date: 2016-04-09 Impact factor: 8.661