| Literature DB >> 23564049 |
Vincenzo Perciavalle1, Richard Apps, Vlastislav Bracha, José M Delgado-García, Alan R Gibson, Maria Leggio, Andrew J Carrel, Nadia Cerminara, Marinella Coco, Agnès Gruart, Raudel Sánchez-Campusano.
Abstract
In the present paper, we examine the role of the cerebellar interpositus nucleus (IN) in motor and non-motor domains. Recent findings are considered, and we share the following conclusions: IN as part of the olivo-cortico-nuclear microcircuit is involved in providing powerful timing signals important in coordinating limb movements; IN could participate in the timing and performance of ongoing conditioned responses rather than the generation and/or initiation of such responses; IN is involved in the control of reflexive and voluntary movements in a task- and effector system-dependent fashion, including hand movements and associated upper limb adjustments, for quick effective actions; IN develops internal models for dynamic interactions of the motor system with the external environment for anticipatory control of movement; and IN plays a significant role in the modulation of autonomic and emotional functions.Entities:
Mesh：
Year: 2013 PMID： 23564049 DOI： 10.1007/s12311-013-0464-0
Source DB: PubMed Journal: Cerebellum ISSN： 1473-4222 Impact factor: 3.847