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Literature DB >> 23563625

Multiplexed ionic current sensing with glass nanopores.

Nicholas A W Bell¹, Vivek V Thacker, Silvia Hernández-Ainsa, Maria E Fuentes-Perez, Fernando Moreno-Herrero, Tim Liedl, Ulrich F Keyser.

Abstract

We report a method for simultaneous ionic current measurements of single molecules across up to 16 solid state nanopore channels. Each device, costing less than $20, contains 16 glass nanopores made by laser assisted capillary pulling. We demonstrate simultaneous multichannel detection of double stranded DNA and trapping of DNA origami nanostructures to form hybrid nanopores.

Mesh：

Substances：
Ions
DNA

Year: 2013 PMID： 23563625 DOI： 10.1039/c3lc50069a

Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799

Keyword Cloud
Cited

13 in total

1. Rectification of ion current in nanopipettes by external substrates.

Authors: Niya Sa; Wen-Jie Lan; Wenqing Shi; Lane A Baker
Journal: ACS Nano Date: 2013-12-09 Impact factor: 15.881

2. Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores.

Authors: Nicholas A W Bell; Ulrich F Keyser
Journal: Nat Nanotechnol Date: 2016-04-04 Impact factor: 39.213

Review 3. Lab-on-a-chip electrical multiplexing techniques for cellular and molecular biomarker detection.

Authors: Fan Liu; Liwei Ni; Jiang Zhe
Journal: Biomicrofluidics Date: 2018-04-10 Impact factor: 2.800

4. A Solid-State Hard Microfluidic-Nanopore Biosensor with Multilayer Fluidics and On-Chip Bioassay/Purification Chamber.

Authors: Nitinun Varongchayakul; Joseph Hersey; Allison Squires; Amit Meller; Mark Grinstaff
Journal: Adv Funct Mater Date: 2018-10-16 Impact factor: 18.808

Multiplexed ionic current sensing with glass nanopores.

1. Rectification of ion current in nanopipettes by external substrates.

2. Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores.

Review 3. Lab-on-a-chip electrical multiplexing techniques for cellular and molecular biomarker detection.

4. A Solid-State Hard Microfluidic-Nanopore Biosensor with Multilayer Fluidics and On-Chip Bioassay/Purification Chamber.

5. Direction- and Salt-Dependent Ionic Current Signatures for DNA Sensing with Asymmetric Nanopores.

6. Ionic conductivity, structural deformation, and programmable anisotropy of DNA origami in electric field.

Review 7. Recent advances in integrated solid-state nanopore sensors.

8. Specific protein detection using designed DNA carriers and nanopores.

9. Label-free optical detection of biomolecular translocation through nanopore arrays.

10. Quantifying Nanomolar Protein Concentrations Using Designed DNA Carriers and Solid-State Nanopores.