| Literature DB >> 23563535 |
Masumi Iijima1, Mikako Yamamoto, Nobuo Yoshimoto, Tomoaki Niimi, Shun'ichi Kuroda.
Abstract
The bio-nanocapsules displaying about 240 molecules of immunoglobulin G Fc-binding Z domains (ZZ-BNCs) enhanced the signals of enzyme-linked immunosorbent assay by tethering the Fc regions of secondary antibodies (Abs), which were eliminated using high-molecular mass enzymes (e.g., alkaline phosphatase). By way of optimizing the distance between enzymes and Abs, ZZ-BNCs improved sensitivity independently of enzymes.Mesh:
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Year: 2013 PMID: 23563535 DOI: 10.1271/bbb.120760
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN: 0916-8451 Impact factor: 2.043