Literature DB >> 23563183

Sustainable production of biologically active molecules of marine based origin.

Patrick M Murray1, Siobhan Moane, Catherine Collins, Tanya Beletskaya, Olivier P Thomas, Alysson W F Duarte, Fernando S Nobre, Ifeloju O Owoyemi, Fernando C Pagnocca, L D Sette, Edward McHugh, Eric Causse, Paula Pérez-López, Gumersindo Feijoo, Ma T Moreira, Juan Rubiolo, Marta Leirós, Luis M Botana, Susete Pinteus, Celso Alves, André Horta, Rui Pedrosa, Clayton Jeffryes, Spiros N Agathos, Celine Allewaert, Annick Verween, Wim Vyverman, Ivan Laptev, Sergei Sineoky, Angela Bisio, Renata Manconi, Fabio Ledda, Mario Marchi, Roberto Pronzato, Daniel J Walsh.   

Abstract

The marine environment offers both economic and scientific potential which are relatively untapped from a biotechnological point of view. These environments whilst harsh are ironically fragile and dependent on a harmonious life form balance. Exploitation of natural resources by exhaustive wild harvesting has obvious negative environmental consequences. From a European industry perspective marine organisms are a largely underutilised resource. This is not due to lack of interest but due to a lack of choice the industry faces for cost competitive, sustainable and environmentally conscientious product alternatives. Knowledge of the biotechnological potential of marine organisms together with the development of sustainable systems for their cultivation, processing and utilisation are essential. In 2010, the European Commission recognised this need and funded a collaborative RTD/SME project under the Framework 7-Knowledge Based Bio-Economy (KBBE) Theme 2 Programme 'Sustainable culture of marine microorganisms, algae and/or invertebrates for high value added products'. The scope of that project entitled 'Sustainable Production of Biologically Active Molecules of Marine Based Origin' (BAMMBO) is outlined. Although the Union is a global leader in many technologies, it faces increasing competition from traditional rivals and emerging economies alike and must therefore improve its innovation performance. For this reason innovation is placed at the heart of a European Horizon 2020 Strategy wherein the challenge is to connect economic performance to eco performance. This article provides a synopsis of the research activities of the BAMMBO project as they fit within the wider scope of sustainable environmentally conscientious marine resource exploitation for high-value biomolecules.
Copyright © 2013 Elsevier B.V. All rights reserved.

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Year:  2013        PMID: 23563183     DOI: 10.1016/j.nbt.2013.03.006

Source DB:  PubMed          Journal:  N Biotechnol        ISSN: 1871-6784            Impact factor:   5.079


  15 in total

1.  Asparagopsis armata and Sphaerococcus coronopifolius as a natural source of antimicrobial compounds.

Authors:  Susete Pinteus; Celso Alves; Hugo Monteiro; Ernesto Araújo; André Horta; Rui Pedrosa
Journal:  World J Microbiol Biotechnol       Date:  2015-01-15       Impact factor: 3.312

2.  Antitumor and antimicrobial potential of bromoditerpenes isolated from the red alga, Sphaerococcus coronopifolius.

Authors:  Daniel Rodrigues; Celso Alves; André Horta; Susete Pinteus; Joana Silva; Gérald Culioli; Olivier P Thomas; Rui Pedrosa
Journal:  Mar Drugs       Date:  2015-01-26       Impact factor: 5.118

3.  High cytotoxicity and anti-proliferative activity of algae extracts on an in vitro model of human hepatocellular carcinoma.

Authors:  Celso Alves; Susete Pinteus; André Horta; Rui Pedrosa
Journal:  Springerplus       Date:  2016-08-12

4.  A new species of Agelas from the Zanzibar Archipelago, western Indian Ocean (Porifera, Demospongiae).

Authors:  Renata Manconi; Roberto Pronzato; Erica Perino
Journal:  Zookeys       Date:  2016-01-14       Impact factor: 1.546

5.  Antioxidant and Cytoprotective Activities of Fucus spiralis Seaweed on a Human Cell in Vitro Model.

Authors:  Susete Pinteus; Joana Silva; Celso Alves; André Horta; Olivier P Thomas; Rui Pedrosa
Journal:  Int J Mol Sci       Date:  2017-01-29       Impact factor: 5.923

6.  Neuroprotective effects of seaweeds against 6-hydroxidopamine-induced cell death on an in vitro human neuroblastoma model.

Authors:  Joana Silva; Celso Alves; Susete Pinteus; Susana Mendes; Rui Pedrosa
Journal:  BMC Complement Altern Med       Date:  2018-02-14       Impact factor: 3.659

7.  Algae from Portuguese Coast Presented High Cytotoxicity and Antiproliferative Effects on an In vitro Model of Human Colorectal Cancer.

Authors:  Celso Alves; Susete Pinteus; Ana Rodrigues; André Horta; Rui Pedrosa
Journal:  Pharmacognosy Res       Date:  2018 Jan-Mar

8.  Antioxidant and antimicrobial potential of the Bifurcaria bifurcata epiphytic bacteria.

Authors:  André Horta; Susete Pinteus; Celso Alves; Nádia Fino; Joana Silva; Sara Fernandez; Américo Rodrigues; Rui Pedrosa
Journal:  Mar Drugs       Date:  2014-03-24       Impact factor: 5.118

Review 9.  Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.

Authors:  Javier Rocha-Martin; Catriona Harrington; Alan D W Dobson; Fergal O'Gara
Journal:  Mar Drugs       Date:  2014-06-10       Impact factor: 5.118

Review 10.  Marine-derived fungi: diversity of enzymes and biotechnological applications.

Authors:  Rafaella C Bonugli-Santos; Maria R Dos Santos Vasconcelos; Michel R Z Passarini; Gabriela A L Vieira; Viviane C P Lopes; Pedro H Mainardi; Juliana A Dos Santos; Lidia de Azevedo Duarte; Igor V R Otero; Aline M da Silva Yoshida; Valker A Feitosa; Adalberto Pessoa; Lara D Sette
Journal:  Front Microbiol       Date:  2015-04-10       Impact factor: 5.640

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