Literature DB >> 23562070

How is the hungry brain like a sieve?

Martin G Myers1.   

Abstract

Whether some hypothalamic neurons have direct access to circulating metabolic cues represents a crucial question that has been intensely debated. New findings reveal that fasting promotes "leakiness" of some hypothalamic blood vessels, increasing the access of circulating factors to certain hypothalamic neurons that control feeding (Langlet et al., 2013).
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Year:  2013        PMID: 23562070      PMCID: PMC3763718          DOI: 10.1016/j.cmet.2013.03.007

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  9 in total

1.  High calorie diet triggers hypothalamic angiopathy.

Authors:  Chun-Xia Yi; Martin Gericke; Martin Krüger; Anneke Alkemade; Dhiraj G Kabra; Sophie Hanske; Jessica Filosa; Paul Pfluger; Nathan Bingham; Stephen C Woods; James Herman; Andries Kalsbeek; Marcus Baumann; Richard Lang; Javier E Stern; Ingo Bechmann; Matthias H Tschöp
Journal:  Mol Metab       Date:  2012-08-09       Impact factor: 7.422

Review 2.  Central nervous system control of metabolism.

Authors:  Martin G Myers; David P Olson
Journal:  Nature       Date:  2012-11-15       Impact factor: 49.962

Review 3.  Central nervous system control of food intake and body weight.

Authors:  G J Morton; D E Cummings; D G Baskin; G S Barsh; M W Schwartz
Journal:  Nature       Date:  2006-09-21       Impact factor: 49.962

4.  Leptin enters the brain by a saturable system independent of insulin.

Authors:  W A Banks; A J Kastin; W Huang; J B Jaspan; L M Maness
Journal:  Peptides       Date:  1996       Impact factor: 3.750

5.  Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region.

Authors:  Nasren Maolood; Björn Meister
Journal:  J Chem Neuroanat       Date:  2008-12-25       Impact factor: 3.052

Review 6.  From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior.

Authors:  Kevin W Williams; Joel K Elmquist
Journal:  Nat Neurosci       Date:  2012-09-25       Impact factor: 24.884

7.  Protein components of the blood-brain barrier (BBB) in the mediobasal hypothalamus.

Authors:  Ebba Norsted; Burçak Gömüç; Björn Meister
Journal:  J Chem Neuroanat       Date:  2008-06-18       Impact factor: 3.052

8.  Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting.

Authors:  Fanny Langlet; Barry E Levin; Serge Luquet; Massimiliano Mazzone; Andrea Messina; Ambrose A Dunn-Meynell; Eglantine Balland; Amelie Lacombe; Daniele Mazur; Peter Carmeliet; Sebastien G Bouret; Vincent Prevot; Bénédicte Dehouck
Journal:  Cell Metab       Date:  2013-04-02       Impact factor: 27.287

9.  Differential accessibility of circulating leptin to individual hypothalamic sites.

Authors:  Miro Faouzi; Rebecca Leshan; Marie Björnholm; Thomas Hennessey; Justin Jones; Heike Münzberg
Journal:  Endocrinology       Date:  2007-08-09       Impact factor: 4.736

  9 in total
  3 in total

Review 1.  Molecular and cellular regulation of hypothalamic melanocortin neurons controlling food intake and energy metabolism.

Authors:  M Koch; T L Horvath
Journal:  Mol Psychiatry       Date:  2014-04-15       Impact factor: 15.992

2.  Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain.

Authors:  Fanny Langlet; Amandine Mullier; Sebastien G Bouret; Vincent Prevot; Benedicte Dehouck
Journal:  J Comp Neurol       Date:  2013-10-15       Impact factor: 3.215

3.  Flipping the tanycyte switch: how circulating signals gain direct access to the metabolic brain.

Authors:  Vincent Prevot; Fanny Langlet; Benedicte Dehouck
Journal:  Aging (Albany NY)       Date:  2013-05       Impact factor: 5.682

  3 in total

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