| Literature DB >> 23560725 |
Xianjie Chen1, Hui Chen, Xun Ji, Hualiang Jiang, Zhu-Jun Yao, Hong Liu.
Abstract
An asymmetric organo- and gold-catalyzed one-pot sequential Mannich/hydroamination reaction has been developed. Using this protocol, spiro[pyrrolidin-3,2'-oxindole] derivatives were synthesized in good yields (up to 91%) and excellent enantioselectivities (up to 97% ee).Entities:
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Year: 2013 PMID： 23560725 DOI： 10.1021/ol4004542
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005