Literature DB >> 23560617

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.

Giancarlo Aldini1, Giulio Vistoli, Milan Stefek, N Chondrogianni, Tilman Grune, Jolanta Sereikaite, Izabela Sadowska-Bartosz, Grzegorz Bartosz.   

Abstract

The advanced glycoxidation end products (AGEs) and lipoxidation end products (ALEs) contribute to the development of diabetic complications and of other pathologies. The review discusses the possibilities of counteracting the formation and stimulating the degradation of these species by pharmaceuticals and natural compounds. The review discusses inhibitors of ALE and AGE formation, cross-link breakers, ALE/AGE elimination by enzymes and proteolytic systems, receptors for advanced glycation end products (RAGEs) and blockade of the ligand-RAGE axis.

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Year:  2013        PMID： 23560617     DOI： 10.3109/10715762.2013.792926

Source DB:  PubMed          Journal:  Free Radic Res        ISSN： 1029-2470


  40 in total

Review 1.  Prevention of non-enzymatic glycosylation (glycation): Implication in the treatment of diabetic complication.

Authors:  H Younus; S Anwar
Journal:  Int J Health Sci (Qassim)       Date:  2016-04

2.  Antioxidant action of 3-mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid, an efficient aldose reductase inhibitor, in a 1,1'-diphenyl-2-picrylhydrazyl assay and in the cellular system of isolated erythrocytes exposed to tert-butyl hydroperoxide.

Authors:  Marta Soltesova Prnova; Jana Ballekova; Magdalena Majekova; Milan Stefek
Journal:  Redox Rep       Date:  2015-06-11       Impact factor: 4.412

Review 3.  Cellular mechanisms and consequences of glycation in atherosclerosis and obesity.

Authors:  Raquel López-Díez; Alexander Shekhtman; Ravichandran Ramasamy; Ann Marie Schmidt
Journal:  Biochim Biophys Acta       Date:  2016-05-08

Review 4.  Vascular endothelium in diabetes.

Authors:  Michael S Goligorsky
Journal:  Am J Physiol Renal Physiol       Date:  2016-11-16

5.  Insights into the effects of N-glycosylation on the characteristics of the VC1 domain of the human receptor for advanced glycation end products (RAGE) secreted by Pichia pastoris.

Authors:  Genny Degani; Alberto Barbiroli; Paula Magnelli; Stefania Digiovanni; Alessandra Altomare; Giancarlo Aldini; Laura Popolo
Journal:  Glycoconj J       Date:  2019-01-05       Impact factor: 2.916

6.  Effect of (-)-epigallocatechin-3-gallate on glucose-induced human serum albumin glycation.

Authors:  M Li; A E Hagerman
Journal:  Free Radic Res       Date:  2015-03-20

7.  Defense against Reactive Carbonyl Species Involves at Least Three Subcellular Compartments Where Individual Components of the System Respond to Cellular Sugar Status.

Authors:  Jessica Schmitz; Isabell C Dittmar; Jörn D Brockmann; Marc Schmidt; Meike Hüdig; Alessandro W Rossoni; Veronica G Maurino
Journal:  Plant Cell       Date:  2017-11-17       Impact factor: 11.277

8.  A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress.

Authors:  Ethan J Anderson; Giulio Vistoli; Lalage A Katunga; Katsuhiko Funai; Luca Regazzoni; T Blake Monroe; Ettore Gilardoni; Luca Cannizzaro; Mara Colzani; Danilo De Maddis; Giuseppe Rossoni; Renato Canevotti; Stefania Gagliardi; Marina Carini; Giancarlo Aldini
Journal:  J Clin Invest       Date:  2018-10-22       Impact factor: 14.808

9.  Lipid peroxidation derived reactive carbonyl species in free and conjugated forms as an index of lipid peroxidation: limits and perspectives.

Authors:  Alessandra Altomare; Giovanna Baron; Erica Gianazza; Cristina Banfi; Marina Carini; Giancarlo Aldini
Journal:  Redox Biol       Date:  2021-02-17       Impact factor: 11.799

Review 10.  Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications.

Authors:  Lucia Kovacikova; Marta Soltesova Prnova; Magdalena Majekova; Andrej Bohac; Cimen Karasu; Milan Stefek
Journal:  Molecules       Date:  2021-05-12       Impact factor: 4.411
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