| Literature DB >> 23560611 |
Briar J Naysmith1, Margaret A Brimble.
Abstract
A highly convergent synthesis of the griseusin B scaffold is described. The key step involves an efficient one-pot Hauser-Kraus annulation-methylation-double deprotection-spirocyclization sequence that directly affords the target parent tetracyclic ring system.Mesh：
Substances：
Year: 2013 PMID： 23560611 DOI： 10.1021/ol400686f
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005