Literature DB >> 23558695

The role of Nrf2 in the attenuation of cardiovascular disease.

Danielle J Reuland1, Joe M McCord, Karyn L Hamilton.   

Abstract

Oxidative stress is a component of many human diseases, including cardiovascular diseases (CVD). Exercise and various phytochemicals activate nuclear factor (erythroid-derived 2)-like 2 (Nrf2), the master regulator of antioxidant defenses, and attenuate CVD. This review highlights Nrf2 regulation by exercise and phytochemicals and the role of Nrf2 as a therapeutic target in CVD.

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Year:  2013        PMID： 23558695     DOI： 10.1097/JES.0b013e3182948a1e

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN： 0091-6331            Impact factor:   6.230


  20 in total

1.  Exercise training causes differential changes in gene expression in diaphragm arteries and 2A arterioles of obese rats.

Authors:  M Harold Laughlin; Jaume Padilla; Nathan T Jenkins; Pamela K Thorne; Jeffrey S Martin; R Scott Rector; Sadia Akter; J Wade Davis
Journal:  J Appl Physiol (1985)       Date:  2015-07-16

2.  Exercise-induced differential changes in gene expression among arterioles of skeletal muscles of obese rats.

Authors:  M Harold Laughlin; Jaume Padilla; Nathan T Jenkins; Pamela K Thorne; Jeffrey S Martin; R Scott Rector; Sadia Akter; J Wade Davis
Journal:  J Appl Physiol (1985)       Date:  2015-07-16

Review 3.  Modulation of angiotensin II signaling following exercise training in heart failure.

Authors:  Irving H Zucker; Harold D Schultz; Kaushik P Patel; Hanjun Wang
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-02-13       Impact factor: 4.733

Review 4.  Nutraceuticals as a potential adjunct therapy toward improving vascular health in CKD.

Authors:  Nicholas T Kruse
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2019-10-02       Impact factor: 3.619

5.  Danshensu protects isolated heart against ischemia reperfusion injury through activation of Akt/ERK1/2/Nrf2 signaling.

Authors:  Jiahui Yu; Lingyan Wang; Mary Akinyi; Yuhong Li; Zhenzhen Duan; Yan Zhu; Guanwei Fan
Journal:  Int J Clin Exp Med       Date:  2015-09-15

6.  Chrysin protects cardiac H9c2 cells against H2O2-induced endoplasmic reticulum stress by up-regulating the Nrf2/PERK pathway.

Authors:  Subramani Yuvaraj; Arumugam Kalaiselvi Ajeeth; Shanavas Syed Mohamed Puhari; Albert Abhishek; Tharmarajan Ramprasath; Varadaraj Vasudevan; Narasimman Vignesh; Govindan Sadasivam Selvam
Journal:  Mol Cell Biochem       Date:  2022-08-09       Impact factor: 3.842

Review 7.  Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.

Authors:  Alexander G Panossian; Thomas Efferth; Alexander N Shikov; Olga N Pozharitskaya; Kenny Kuchta; Pulok K Mukherjee; Subhadip Banerjee; Michael Heinrich; Wanying Wu; De-An Guo; Hildebert Wagner
Journal:  Med Res Rev       Date:  2020-10-25       Impact factor: 12.944

8.  Tanshinone I Inhibits Oxidative Stress-Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling.

Authors:  Yu-Ting Wu; Ling-Peng Xie; Yue Hua; Hong-Lin Xu; Guang-Hong Chen; Xin Han; Zhang-Bin Tan; Hui-Jie Fan; Hong-Mei Chen; Jun Li; Bin Liu; Ying-Chun Zhou
Journal:  Front Pharmacol       Date:  2021-05-18       Impact factor: 5.810

9.  Exercise training upregulates Nrf2 protein in the rostral ventrolateral medulla of mice with heart failure.

Authors:  Ahmed M Wafi; Li Yu; Lie Gao; Irving H Zucker
Journal:  J Appl Physiol (1985)       Date:  2019-09-26

Review 10.  Cardiovasomobility: an integrative understanding of how disuse impacts cardiovascular and skeletal muscle health.

Authors:  Joel D Trinity; Micah J Drummond; Caitlin C Fermoyle; Alec I McKenzie; Mark A Supiano; Russell S Richardson
Journal:  J Appl Physiol (1985)       Date:  2022-02-03
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