OBJECTIVE: The Recovery Management paradigm provides a conceptual framework for the examination of joint impact of a focal treatment and post-treatment service utilization on substance abuse treatment outcomes. We test this framework by examining the interactive effects of a treatment for comorbid PTSD and substance use, Seeking Safety, and post-treatment Twelve-Step Affiliation (TSA) on alcohol and cocaine use. METHOD: Data from 353 women in a six-site, randomized controlled effectiveness trial within the NIDA Clinical Trials Network were analyzed under latent class pattern mixture modeling. LCPMM was used to model variation in Seeking Safety by TSA interaction effects on alcohol and cocaine use. RESULTS: Significant reductions in alcohol use among women in Seeking Safety (compared to health education) were observed; women in the Seeking Safety condition who followed up with TSA had the greatest reductions over time in alcohol use. Reductions in cocaine use over time were also observed but did not differ between treatment conditions nor were there interactions with post-treatment TSA. CONCLUSIONS: Findings advance understanding of the complexities for treatment and continuing recovery processes for women with PTSD and SUDs, and further support the chronic disease model of addiction.
RCT Entities:
OBJECTIVE: The Recovery Management paradigm provides a conceptual framework for the examination of joint impact of a focal treatment and post-treatment service utilization on substance abuse treatment outcomes. We test this framework by examining the interactive effects of a treatment for comorbid PTSD and substance use, Seeking Safety, and post-treatment Twelve-Step Affiliation (TSA) on alcohol and cocaine use. METHOD: Data from 353 women in a six-site, randomized controlled effectiveness trial within the NIDA Clinical Trials Network were analyzed under latent class pattern mixture modeling. LCPMM was used to model variation in Seeking Safety by TSA interaction effects on alcohol and cocaine use. RESULTS: Significant reductions in alcohol use among women in Seeking Safety (compared to health education) were observed; women in the Seeking Safety condition who followed up with TSA had the greatest reductions over time in alcohol use. Reductions in cocaine use over time were also observed but did not differ between treatment conditions nor were there interactions with post-treatment TSA. CONCLUSIONS: Findings advance understanding of the complexities for treatment and continuing recovery processes for women with PTSD and SUDs, and further support the chronic disease model of addiction.
Authors: Denise A Hien; Aimee N C Campbell; Lesia M Ruglass; Lissette Saavedra; Abigail G Mathews; Grace Kiriakos; Antonio Morgan-Lopez Journal: J Subst Abuse Treat Date: 2015-04-07
Authors: Margaret M Gorvine; Tiffany F Haynes; S Alexandra Marshall; Cari J Clark; Nakita N Lovelady; Nickolas D Zaller Journal: Integr Med (Encinitas) Date: 2021-06
Authors: Antonio A Morgan-López; Heather L McDaniel; Catherine P Bradshaw; Lissette M Saavedra; John E Lochman; Chelsea A Kaihoi; Nicole P Powell; Lixin Qu; Anna C Yaros Journal: Contemp Clin Trials Date: 2022-02-14 Impact factor: 2.261
Authors: Denise Hien; Frankie Kropp; Elizabeth A Wells; Aimee Campbell; Mary Hatch-Maillette; Candace Hodgkins; Therese Killeen; Teresa Lopez-Castro; Antonio Morgan-Lopez; Lesia M Ruglass; Lissette Saavedra; Edward V Nunes Journal: J Subst Abuse Treat Date: 2020-03