| Literature DB >> 23556427 |
George Procopiou1, William Lewis, Gareth Harbottle, Robert A Stockman.
Abstract
The cycloaddition of chiral tert-butanesulfinimines with trimethylenemethane is found to give facile access to methylene-pyrrolidines with good yields and diastereoselectivities. The full scope of the cycloaddition is explored, and a range of transformations of the formed methylenepyrrolidines to give a range of functionalized chiral pyrrolidines is presented.Entities:
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Year: 2013 PMID： 23556427 DOI： 10.1021/ol400720b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005