Literature DB >> 23555439

CHADS2 Score is a Poor Predictor of Non-cerebral Acute Arterial Occlusion in Patients with Non-valvular Atrial Fibrillation.

Kota Yamamoto1, Tadashi Kitaoka, Harunobu Matsumoto, Juno Deguchi, Michio Shiibashi, Osamu Sato.   

Abstract

OBJECTIVE: The CHADS2 score is a stroke risk stratification scheme in patients with non-valvular atrial fibrillation (NVAF). The aim of this study was to determine whether the CHADS2 score can help to predict the risk of non-cerebral acute arterial embolism.
MATERIALS AND METHODS: One hundred and seventeen patients who underwent surgery for non-cerebral acute arterial embolism with NVAF between 1997 and 2009 were enrolled in the cross sectional study. The CHADS2 score of each patient was calculated at the onset of symptoms. The distribution of the CHADS2 score was compared with that of other studies analyzing patients with stroke.
RESULTS: The perioperative mortality was 11.1%. A comparison of patients with stroke revealed that our distribution curves were significantly shifted to the left, showing that the CHADS2 score did better in predicting stroke than non-cerebral embolism. On the other hand, the distribution in our series coincides with that of NVAF patients in general. These results indicated that the risk of non-cerebral embolism occurs at the same rate regardless of the CHADS2 score.
CONCLUSIONS: The CHADS2 scoring system seems to be an unreliable predictor of non-cerebral embolism, and may not contribute in avoiding potentially life-threatening acute arterial occlusion of the peripheral artery.

Entities:  

Keywords:  CHADS2 score; anticoagulation; non-cerebral embolism; non-valvular atrial fibrillation

Year:  2011        PMID: 23555439      PMCID: PMC3595835          DOI: 10.3400/avd.oa.11.00004

Source DB:  PubMed          Journal:  Ann Vasc Dis        ISSN: 1881-641X


  14 in total

1.  Patients with nonvalvular atrial fibrillation at low risk of stroke during treatment with aspirin: Stroke Prevention in Atrial Fibrillation III Study. The SPAF III Writing Committee for the Stroke Prevention in Atrial Fibrillation Investigators.

Authors: 
Journal:  JAMA       Date:  1998 Apr 22-29       Impact factor: 56.272

2.  Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation.

Authors:  B F Gage; A D Waterman; W Shannon; M Boechler; M W Rich; M J Radford
Journal:  JAMA       Date:  2001-06-13       Impact factor: 56.272

3.  Lone atrial fibrillation in elderly persons: a marker for cardiovascular risk.

Authors:  S L Kopecky; B J Gersh; M D McGoon; C P Chu; D M Ilstrup; J H Chesebro; J P Whisnant
Journal:  Arch Intern Med       Date:  1999-05-24

4.  Acute thrombo-embolic occlusion of the superior mesenteric artery: a prospective study in a well defined population.

Authors:  S Acosta; M Björck
Journal:  Eur J Vasc Endovasc Surg       Date:  2003-08       Impact factor: 7.069

Review 5.  Atrial fibrillation and coagulation: who and when?

Authors:  David Fitzmaurice
Journal:  Blood Rev       Date:  2009-08-25       Impact factor: 8.250

6.  Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin.

Authors:  Brian F Gage; Carl van Walraven; Lesly Pearce; Robert G Hart; Peter J Koudstaal; B S P Boode; Palle Petersen
Journal:  Circulation       Date:  2004-10-11       Impact factor: 29.690

7.  Atrial fibrillation significantly increases total mortality and stroke risk beyond that conveyed by the CHADS2 risk factors.

Authors:  Mark A Crandall; Benjamin D Horne; John D Day; Jeffrey L Anderson; Joseph B Muhlestein; Brian G Crandall; J Peter Weiss; Jeffrey S Osborne; Donald L Lappé; T Jared Bunch
Journal:  Pacing Clin Electrophysiol       Date:  2009-08       Impact factor: 1.976

8.  Warfarin treatment in patients with atrial fibrillation: observing outcomes associated with varying levels of INR control.

Authors:  Christopher Ll Morgan; Phil McEwan; Andrzej Tukiendorf; Paul A Robinson; Andreas Clemens; Jonathan M Plumb
Journal:  Thromb Res       Date:  2008-12-04       Impact factor: 3.944

9.  Prevalence, age distribution, and gender of patients with atrial fibrillation. Analysis and implications.

Authors:  W M Feinberg; J L Blackshear; A Laupacis; R Kronmal; R G Hart
Journal:  Arch Intern Med       Date:  1995-03-13

10.  Predictors of major vascular events in patients with a transient ischemic attack or minor ischemic stroke and with nonrheumatic atrial fibrillation. European Atrial Fibrillation Trial (EAFT) Study Group.

Authors:  J C van Latum; P J Koudstaal; G S Venables; J van Gijn; L J Kappelle; A Algra
Journal:  Stroke       Date:  1995-05       Impact factor: 7.914

View more
  2 in total

1.  A Case of Embolism due to a Floating Thrombus Migrating from the Left Atrial Appendage to the Ostium of the Celiac Artery.

Authors:  Takashi Ando; Hiroyuki Abe; Daijun Ro
Journal:  Ann Vasc Dis       Date:  2012

2.  Is CHA2DS2-VASc Score Different in Patients with Non-valvular Atrial Fibrillation Suffering from Cerebral and Non-cerebral Thromboembolism?CHA2DS2-VASc Score in Thromboembolism.

Authors:  Sadık Volkan Emren; Fatih Ada; Mustafa Aldemir; Evren Tecer; Görkem Çarşanba; Damla Çelik; Ersin Çelik; Ersel Onrat
Journal:  J Atr Fibrillation       Date:  2017-08-31
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.