| Literature DB >> 23554207 |
Romaric Nzoumbou-Boko1, Mariette Dethoua, Fréderic Gabriel, Alain Buguet, Raymond Cespuglio, Pierrette Courtois, Sylvie Daulouède, Bernard Bouteille, Stéphane Ngampo, Ghislain Mpandzou, Silla Semballa, Philippe Vincendeau.
Abstract
Arginase serum levels were increased in human African trypanosomiasis patients and returned to control values after treatment. Arginase hydrolyzes l-arginine to l-ornithine, which is essential for parasite growth. Moreover, l-arginine depletion impairs immune functions. Arginase may be considered as a biomarker for treatment efficacy.Entities:
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Year: 2013 PMID： 23554207 PMCID： PMC3697696 DOI： 10.1128/JCM.03371-12
Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948