Literature DB >> 23554128

Homer proteins in Ca²⁺ entry.

Isaac Jardin1, José J López, Alejandro Berna-Erro, Ginés M Salido, Juan A Rosado.   

Abstract

The Homer family of proteins consists of three adaptor proteins, Homer1, Homer2 and Homer3, each with various isoforms. Homer1 family presents an EVH1 domain, a coiled coil domain and two leucine zipper domains. Homer proteins regulate a number of Ca2+-handling proteins, including transient receptor potential channels and other Ca2+-permeable channels, ionotropic and metabotropic glutamate receptors, shank scaffolding proteins or endoplasmic reticulum Ca2+ release channels. This review article focuses on the association of Homer 1 proteins with Ca2+-handling proteins and their role on intracellular Ca2+-homeostasis.
Copyright © 2013 International Union of Biochemistry and Molecular Biology, Inc.

Entities:  

Keywords:  Homer; IP3R; PMCA; TRP channels

Mesh：

Substances：

Year:  2013        PMID： 23554128     DOI： 10.1002/iub.1162

Source DB:  PubMed          Journal:  IUBMB Life        ISSN： 1521-6543            Impact factor:   3.885


  11 in total

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Review 8.  TRPs in Pain Sensation.

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10.  The mTORC2 Regulator Homer1 Modulates Protein Levels and Sub-Cellular Localization of the CaSR in Osteoblast-Lineage Cells.

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