Literature DB >> 23552753

[A case of mucinous tubular and spindle cell carcinoma of the kidney].

Katsuyuki Saito1, Makoto Shimada, Katsuki Inoue, Kazuhiko Shiiki, Masakazu Nagata, Yuichiro Ogawa, Eiji Matsubara, Tomoko Maeda, Yuki Matsumoto, Toshiaki Kunimura, Tetsuya Mikogami.   

Abstract

Mucinous tubular and spindle cell carcinoma (MTSCC) is a distinct entity in the World Health Organization classification of kidney tumors since 2004. Herein, we report a case of a patient with MTSCC of the kidney. A 48-year-man visited our hospital with a chief complaint of occult blood in his urine, confirmed by urine occult blood reaction. Computed tomography revealed a solid tumor in the right kidney. The tumor was 40×38 mm in length and was slightly enhanced (cT1aN0M0). Therefore, we performed radical nephrectomy. On analysis of the resected specimen, we found that the number of comparatively small malignant cells had increased markedly, forming branched tubular cuboidal cells. Further more, positive results were obtained on staining the stroma with both PAS and alcian blue stains characteristic of papillary renal cell carcinoma ; however, extracellular mucinous material was found to be depleted. Therefore, we needed to differentiate between papillary renal cell carcinoma and MTSCC. Finally, on the basis of the immunohistochemical staining results-vimentin (+), CK34βE12 (-), and CD10 (-)-MTSCC was confirmed.

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Year:  2013        PMID: 23552753

Source DB:  PubMed          Journal:  Hinyokika Kiyo        ISSN: 0018-1994


  2 in total

Review 1.  Renal mucinous tubular and spindle cell carcinoma: report of four cases and literature review.

Authors:  Hui Wang; Jun Xie; Changqing Lu; Dachuan Zhang; Jingting Jiang
Journal:  Int J Clin Exp Pathol       Date:  2015-03-01

2.  Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: A case report.

Authors:  Toru Sakatani; Yoshinaga Okumura; Naoto Kuroda; Toshihiro Magaribuchi; Yorika Nakano; Toshiaki Shirahase; Jun Watanabe; Yoji Taki; Mitsuhiko Okigaki; Susumu Ikehara; Yasushi Adachi
Journal:  Mol Clin Oncol       Date:  2017-09-29
  2 in total

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