BACKGROUND: Socioeconomic deprivation is associated with higher renal replacement therapy acceptance rates in the UK but lower rates of living kidney transplantation. This study examines donor-recipient relationship patterns with socioeconomic deprivation in the white population of England. METHODS: Demographic characteristics of all white live renal transplant donors and recipients between 2001 and 2010 in England were analyzed. Patterns of donor-recipient relationship were analyzed to see whether they differed according to an ecological measure of socioeconomic status (Index of Multiple Deprivation). Group comparisons were performed using chi-square tests and multivariable logistic regression. RESULTS: Sources of living kidney transplants differed with deprivation (p < 0.001). Recipients living in poorer areas were more likely to receive a kidney from a sibling, child, and "other relative" donor and less likely from spouses/partners. Logistic regression suggested differences seen with spouse/partner donations with deprivation were explained by differences in the age and gender of the recipients. CONCLUSIONS: The source of living kidneys differs by level of area deprivation. Given the disparity in rates of living kidney transplants between the most and least socioeconomically deprived, there is a need to understand the reasons behind these observed relationship differences, with the aim of increasing transplantation rates in the most deprived.
BACKGROUND: Socioeconomic deprivation is associated with higher renal replacement therapy acceptance rates in the UK but lower rates of living kidney transplantation. This study examines donor-recipient relationship patterns with socioeconomic deprivation in the white population of England. METHODS: Demographic characteristics of all white live renal transplant donors and recipients between 2001 and 2010 in England were analyzed. Patterns of donor-recipient relationship were analyzed to see whether they differed according to an ecological measure of socioeconomic status (Index of Multiple Deprivation). Group comparisons were performed using chi-square tests and multivariable logistic regression. RESULTS: Sources of living kidney transplants differed with deprivation (p < 0.001). Recipients living in poorer areas were more likely to receive a kidney from a sibling, child, and "other relative" donor and less likely from spouses/partners. Logistic regression suggested differences seen with spouse/partner donations with deprivation were explained by differences in the age and gender of the recipients. CONCLUSIONS: The source of living kidneys differs by level of area deprivation. Given the disparity in rates of living kidney transplants between the most and least socioeconomically deprived, there is a need to understand the reasons behind these observed relationship differences, with the aim of increasing transplantation rates in the most deprived.
Authors: Anna Francis; Madeleine Didsbury; Wai H Lim; Siah Kim; Sarah White; Jonathan C Craig; Germaine Wong Journal: Pediatr Nephrol Date: 2015-12-21 Impact factor: 3.714
Authors: Lucy A Plumb; Manish D Sinha; Anna Casula; Carol D Inward; Stephen D Marks; Fergus J Caskey; Yoav Ben-Shlomo Journal: Clin J Am Soc Nephrol Date: 2021-01-19 Impact factor: 8.237
Authors: Rosalie A Poldervaart; Mirjam Laging; Tessa Royaards; Judith A Kal-van Gestel; Madelon van Agteren; Marry de Klerk; Willij Zuidema; Michiel G H Betjes; Joke I Roodnat Journal: J Transplant Date: 2015-09-02