Literature DB >> 23550966

Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of triterpenoids isolated from leaves and twigs of Gardenia carinata.

Naowarat Kongkum1, Patoomratana Tuchinda, Manat Pohmakotr, Vichai Reutrakul, Pawinee Piyachaturawat, Surawat Jariyawat, Kanoknetr Suksen, Radeekorn Akkarawongsapat, Jitra Kasisit, Chanita Napaswad.   

Abstract

Eight new cycloartane triterpenoids (1-8), named carinatins A-H, and the known compounds secaubryolide (9) and dikamaliartane D (10) were isolated from the leaves and twigs of Gardenia carinata. Their structures were determined on the basis of spectroscopic methods. Cytotoxic, antitopoisomerase IIα, and anti-HIV-1 activities of compounds 1-7, 9, and 10 were investigated.

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Year:  2013        PMID: 23550966     DOI: 10.1021/np3006887

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  3 in total

Review 1.  Recent advances in natural anti-HIV triterpenoids and analogs.

Authors:  Hai-Feng Wu; Susan L Morris-Natschke; Xu-Dong Xu; Mei-Hua Yang; Yung-Yi Cheng; Shi-Shan Yu; Kuo-Hsiung Lee
Journal:  Med Res Rev       Date:  2020-07-14       Impact factor: 12.944

2.  Kleinhospitine E and Cycloartane Triterpenoids from Kleinhovia hospita.

Authors:  Abdul Rahim; Yohei Saito; Katsunori Miyake; Masuo Goto; Chin-Ho Chen; Gemini Alam; Susan Morris-Natschke; Kuo-Hsiung Lee; Kyoko Nakagawa-Goto
Journal:  J Nat Prod       Date:  2018-07-16       Impact factor: 4.050

3.  In Vivo and In Vitro Antimicrobial Activity of Biogenic Silver Nanoparticles against Staphylococcus aureus Clinical Isolates.

Authors:  Nashwah G M Attallah; Engy Elekhnawy; Walaa A Negm; Ismail A Hussein; Fatma Alzahraa Mokhtar; Omnia Momtaz Al-Fakhrany
Journal:  Pharmaceuticals (Basel)       Date:  2022-02-03
  3 in total

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