OBJECTIVE: To investigate the effectiveness of an intervention aimed at improving the case management of eclampsia. DESIGN: A multi-center intervention study. SETTING: Six teaching hospitals in Nigeria. SAMPLE: Clinical records of cases of eclampsia treated before and 1 year after the intervention. METHODS: Doctors and midwives in selected hospitals were re-trained to manage eclampsia using magnesium sulfate according to the Pritchard protocol. MAIN OUTCOME MEASURES: Eclampsia case fatality rates, maternal and perinatal mortality rates before and after the intervention. RESULTS: A total of 219 cases of eclampsia were managed over a 12-month period. There were seven maternal deaths. The post intervention case fatality rate of 3.2% was significantly less than the pre-intervention rate of 15.1% (p < 0.001). The overall maternal and perinatal mortality ratios and rates respectively in the hospitals declined from 1199.2 to 954 per 100,000 deliveries and 141.5 to 129.8 per 1000 births, respectively (p > 0.05). CONCLUSION: An intervention to build the capacity of care-providers to use an evidence-based protocol for the treatment of eclampsia in Nigeria was successful in reducing associated case fatality rate. The increased and widespread use of such an intervention in maternity units might contribute to the reduction of maternal mortality in low-income countries.
OBJECTIVE: To investigate the effectiveness of an intervention aimed at improving the case management of eclampsia. DESIGN: A multi-center intervention study. SETTING: Six teaching hospitals in Nigeria. SAMPLE: Clinical records of cases of eclampsia treated before and 1 year after the intervention. METHODS: Doctors and midwives in selected hospitals were re-trained to manage eclampsia using magnesium sulfate according to the Pritchard protocol. MAIN OUTCOME MEASURES: Eclampsia case fatality rates, maternal and perinatal mortality rates before and after the intervention. RESULTS: A total of 219 cases of eclampsia were managed over a 12-month period. There were seven maternal deaths. The post intervention case fatality rate of 3.2% was significantly less than the pre-intervention rate of 15.1% (p < 0.001). The overall maternal and perinatal mortality ratios and rates respectively in the hospitals declined from 1199.2 to 954 per 100,000 deliveries and 141.5 to 129.8 per 1000 births, respectively (p > 0.05). CONCLUSION: An intervention to build the capacity of care-providers to use an evidence-based protocol for the treatment of eclampsia in Nigeria was successful in reducing associated case fatality rate. The increased and widespread use of such an intervention in maternity units might contribute to the reduction of maternal mortality in low-income countries.
Authors: Musa Abubakar Kana; Henry Victor Doctor; Bárbara Peleteiro; Nuno Lunet; Henrique Barros Journal: BMC Public Health Date: 2015-04-09 Impact factor: 3.295
Authors: Elizabeth Wastnedge; Donald Waters; Sarah R Murray; Brian McGowan; Effie Chipeta; Alinane Linda Nyondo-Mipando; Luis Gadama; Gladys Gadama; Martha Masamba; Monica Malata; Frank Taulo; Queen Dube; Kondwani Kawaza; Patricia Munthali Khomani; Sonia Whyte; Mia Crampin; Bridget Freyne; Jane E Norman; Rebecca M Reynolds Journal: J Glob Health Date: 2021-12-30 Impact factor: 4.413
Authors: Dalau Mukadi Nkamba; Roland Vangu; Moyene Elongi; Laura A Magee; Gilbert Wembodinga; Pierre Bernard; John Ditekemena; Annie Robert Journal: BMC Health Serv Res Date: 2020-10-07 Impact factor: 2.655