Literature DB >> 23549716

Geographical distribution of chronic kidney disease of unknown origin in North Central Region of Sri Lanka.

J M Jayasekara1, D M Dissanayake, S B Adhikari, P Bandara.   

Abstract

OBJECTIVES: In early nineties investigators noticed an alarmingly high incidence of an apparently new form of chronic kidney disease of unknown aetiology (CKD-U) in some parts of Sri Lanka. The aim of the study was to investigate the geographical distribution of CKD-U using GIS and GPS mapping.
METHODS: Community based information was collected from 11,630 patients for GIS mapping using ARC 9.2 software. Based on GIS mapping, two locations were selected for GPS mapping to locate the households of 863 CKD-U patients with reference to reservoirs, irrigation canals and the topography of the areas.
RESULTS: GIS mapping indicated five high prevalence areas of CKD-U. Communities who consumed water from natural springs showed a low prevalence of the disease. GPS mapping showed that most of the affected villages were located below the reservoirs and canals with stagnant irrigated water.
CONCLUSION: Epidemiological data on geographical distribution infers that while older foci of CKD-U are persisting, there is an emergence of new foci with time. The location of the affected villages below the level of the reservoirs/canals may indicate the possibility of draining of irrigated water to the shallow wells of the households, which is the source of drinking water.

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Year:  2013        PMID: 23549716     DOI: 10.4038/cmj.v58i1.5356

Source DB:  PubMed          Journal:  Ceylon Med J        ISSN: 0009-0875


  27 in total

Review 1.  Chronic kidney disease of unknown etiology in Sri Lanka.

Authors:  Senaka Rajapakse; Mitrakrishnan Chrishan Shivanthan; Mathu Selvarajah
Journal:  Int J Occup Environ Health       Date:  2016-07-11

Review 2.  The role of ions, heavy metals, fluoride, and agrochemicals: critical evaluation of potential aetiological factors of chronic kidney disease of multifactorial origin (CKDmfo/CKDu) and recommendations for its eradication.

Authors:  Sunil J Wimalawansa
Journal:  Environ Geochem Health       Date:  2015-10-13       Impact factor: 4.609

3.  Chronic kidney disease of unknown aetiology and ground-water ionicity: study based on Sri Lanka.

Authors:  M W C Dharma-Wardana; Sarath L Amarasiri; Nande Dharmawardene; C R Panabokke
Journal:  Environ Geochem Health       Date:  2014-08-14       Impact factor: 4.609

Review 4.  Role of biomarkers of nephrotoxic acute kidney injury in deliberate poisoning and envenomation in less developed countries.

Authors:  Fahim Mohamed; Zoltan H Endre; Nicholas A Buckley
Journal:  Br J Clin Pharmacol       Date:  2015-05-28       Impact factor: 4.335

5.  Chronic kidney disease of unknown etiology and the effect of multiple-ion interactions.

Authors:  M W C Dharma-Wardana
Journal:  Environ Geochem Health       Date:  2017-09-01       Impact factor: 4.609

Review 6.  Toxic environmental exposures and kidney health in children.

Authors:  Darcy K Weidemann; Virginia M Weaver; Jeffrey J Fadrowski
Journal:  Pediatr Nephrol       Date:  2015-10-12       Impact factor: 3.714

7.  Water quality and chronic kidney disease of unknown aetiology (CKDu) in the dry zone region of Sri Lanka: impacts on well-being of village communities and the way forward.

Authors:  Uthpala Pinto; Bhadranie Thoradeniya; Basant Maheshwari
Journal:  Environ Sci Pollut Res Int       Date:  2019-12-10       Impact factor: 4.223

8.  Cadmium, Chromium, and Lead Uptake Associated Health Risk Assessment of Alternanthera sessilis: A Commonly Consumed Green Leafy Vegetable.

Authors:  W M Dimuthu Nilmini Wijeyaratne; E A Charuni Sewwandi Kumari
Journal:  J Toxicol       Date:  2021-05-17

9.  Endemic chronic kidney disease of unknown etiology in Sri Lanka: Correlation of pathology with clinical stages.

Authors:  S Wijetunge; N V I Ratnatunga; T D J Abeysekera; A W M Wazil; M Selvarajah
Journal:  Indian J Nephrol       Date:  2015 Sep-Oct

10.  A Systematic Review of Renal Pathology in Chronic Kidney Disease of Uncertain Etiology.

Authors:  Sameera Gunawardena; Maleesha Dayaratne; Harshima Wijesinghe; Eranga Wijewickrama
Journal:  Kidney Int Rep       Date:  2021-04-20
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