Literature DB >> 23549610

The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease.

Zhilin Ren1, Liming Yan, Ning Zhang, Yu Guo, Cheng Yang, Zhiyong Lou, Zihe Rao.   

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Year:  2013        PMID： 23549610      PMCID： PMC4875521          DOI： 10.1007/s13238-013-2841-3

Source DB:  PubMed          Journal:  Protein Cell        ISSN： 1674-800X            Impact factor:   14.870


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  12 in total

Review 1.  Virus-encoded proteinases and proteolytic processing in the Nidovirales.

Authors:  J Ziebuhr; E J Snijder; A E Gorbalenya
Journal:  J Gen Virol       Date:  2000-04       Impact factor: 3.891

2.  Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders.

Authors:  Susanna K P Lau; Kenneth S M Li; Alan K L Tsang; Chung-Tong Shek; Ming Wang; Garnet K Y Choi; Rongtong Guo; Beatrice H L Wong; Rosana W S Poon; Carol S F Lam; Sylvia Y H Wang; Rachel Y Y Fan; Kwok-Hung Chan; Bo-Jian Zheng; Patrick C Y Woo; Kwok-Yung Yuen
Journal:  J Virol       Date:  2012-08-29       Impact factor: 5.103

Review 3.  Characterization and inhibition of SARS-coronavirus main protease.

Authors:  Po-Huang Liang
Journal:  Curr Top Med Chem       Date:  2006       Impact factor: 3.295

4.  Structure of the main protease from a global infectious human coronavirus, HCoV-HKU1.

Authors:  Qi Zhao; Shuang Li; Fei Xue; Yilong Zou; Cheng Chen; Mark Bartlam; Zihe Rao
Journal:  J Virol       Date:  2008-06-18       Impact factor: 5.103

5.  Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.

Authors:  Xiaoyu Xue; Hongwei Yu; Haitao Yang; Fei Xue; Zhixin Wu; Wei Shen; Jun Li; Zhe Zhou; Yi Ding; Qi Zhao; Xuejun C Zhang; Ming Liao; Mark Bartlam; Zihe Rao
Journal:  J Virol       Date:  2007-12-19       Impact factor: 5.103

6.  Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs.

Authors:  Kanchan Anand; John Ziebuhr; Parvesh Wadhwani; Jeroen R Mesters; Rolf Hilgenfeld
Journal:  Science       Date:  2003-05-13       Impact factor: 47.728

7.  The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor.

Authors:  Haitao Yang; Maojun Yang; Yi Ding; Yiwei Liu; Zhiyong Lou; Zhe Zhou; Lei Sun; Lijuan Mo; Sheng Ye; Hai Pang; George F Gao; Kanchan Anand; Mark Bartlam; Rolf Hilgenfeld; Zihe Rao
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-29       Impact factor: 11.205

8.  Design of wide-spectrum inhibitors targeting coronavirus main proteases.

Authors:  Haitao Yang; Weiqing Xie; Xiaoyu Xue; Kailin Yang; Jing Ma; Wenxue Liang; Qi Zhao; Zhe Zhou; Duanqing Pei; John Ziebuhr; Rolf Hilgenfeld; Kwok Yung Yuen; Luet Wong; Guangxia Gao; Saijuan Chen; Zhu Chen; Dawei Ma; Mark Bartlam; Zihe Rao
Journal:  PLoS Biol       Date:  2005-09-06       Impact factor: 8.029

9.  New nsp8 isoform suggests mechanism for tuning viral RNA synthesis.

Authors:  Shuang Li; Qi Zhao; Yinjie Zhang; Yang Zhang; Mark Bartlam; Xuemei Li; Zihe Rao
Journal:  Protein Cell       Date:  2010-02-06       Impact factor: 14.870

10.  Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters.

Authors:  Jiun-Jie Shie; Jim-Min Fang; Tun-Hsun Kuo; Chih-Jung Kuo; Po-Huang Liang; Hung-Jyun Huang; Yin-Ta Wu; Jia-Tsrong Jan; Yih-Shyun E Cheng; Chi-Huey Wong
Journal:  Bioorg Med Chem       Date:  2005-09-01       Impact factor: 3.641
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  57 in total

Review 1.  Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease.

Authors:  Jasper F W Chan; Susanna K P Lau; Kelvin K W To; Vincent C C Cheng; Patrick C Y Woo; Kwok-Yung Yuen
Journal:  Clin Microbiol Rev       Date:  2015-04       Impact factor: 26.132

Review 2.  Review on development of potential inhibitors of SARS-CoV-2 main protease (MPro).

Authors:  Soumya Gulab Katre; Alpana Jagdish Asnani; Kumar Pratyush; Nilima Gangadhar Sakharkar; Ashwini Gajanan Bhope; Kanchan Tekram Sawarkar; Vaibhav Santosh Nimbekar
Journal:  Futur J Pharm Sci       Date:  2022-06-21

Review 3.  Recent advances in small-molecular therapeutics for COVID-19.

Authors:  Lei Zhong; Zhipeng Zhao; Xuerun Peng; Jun Zou; Shengyong Yang
Journal:  Precis Clin Med       Date:  2022-09-24

4.  Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors.

Authors:  Andy Kilianski; Anna M Mielech; Xufang Deng; Susan C Baker
Journal:  J Virol       Date:  2013-08-28       Impact factor: 5.103

5.  Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.

Authors:  Zhenming Jin; Xiaoyu Du; Yechun Xu; Yongqiang Deng; Meiqin Liu; Yao Zhao; Bing Zhang; Xiaofeng Li; Leike Zhang; Chao Peng; Yinkai Duan; Jing Yu; Lin Wang; Kailin Yang; Fengjiang Liu; Rendi Jiang; Xinglou Yang; Tian You; Xiaoce Liu; Xiuna Yang; Fang Bai; Hong Liu; Xiang Liu; Luke W Guddat; Wenqing Xu; Gengfu Xiao; Chengfeng Qin; Zhengli Shi; Hualiang Jiang; Zihe Rao; Haitao Yang
Journal:  Nature       Date:  2020-04-09       Impact factor: 49.962

6.  Screening Malaria-box compounds to identify potential inhibitors against SARS-CoV-2 Mpro, using molecular docking and dynamics simulation studies.

Authors:  Shahzaib Ahamad; Hema Kanipakam; Shweta Birla; Md Shaukat Ali; Dinesh Gupta
Journal:  Eur J Pharmacol       Date:  2020-10-24       Impact factor: 4.432

7.  Identification and Development of Therapeutics for COVID-19.

Authors:  Halie M Rando; Nils Wellhausen; Soumita Ghosh; Alexandra J Lee; Anna Ada Dattoli; Fengling Hu; James Brian Byrd; Diane N Rafizadeh; Ronan Lordan; Yanjun Qi; Yuchen Sun; Christian Brueffer; Jeffrey M Field; Marouen Ben Guebila; Nafisa M Jadavji; Ashwin N Skelly; Bharath Ramsundar; Jinhui Wang; Rishi Raj Goel; YoSon Park; Simina M Boca; Anthony Gitter; Casey S Greene
Journal:  mSystems       Date:  2021-11-02       Impact factor: 6.496

8.  The Repurposed Drugs Suramin and Quinacrine Cooperatively Inhibit SARS-CoV-2 3CLpro In Vitro.

Authors:  Raphael J Eberle; Danilo S Olivier; Marcos S Amaral; Ian Gering; Dieter Willbold; Raghuvir K Arni; Monika A Coronado
Journal:  Viruses       Date:  2021-05-10       Impact factor: 5.048

9.  Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus.

Authors:  Laurence Josset; Vineet D Menachery; Lisa E Gralinski; Sudhakar Agnihothram; Pavel Sova; Victoria S Carter; Boyd L Yount; Rachel L Graham; Ralph S Baric; Michael G Katze
Journal:  mBio       Date:  2013-04-30       Impact factor: 7.867

10.  Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus.

Authors:  Anna Lundin; Ronald Dijkman; Tomas Bergström; Nina Kann; Beata Adamiak; Charles Hannoun; Eveline Kindler; Hulda R Jónsdóttir; Doreen Muth; Joeri Kint; Maria Forlenza; Marcel A Müller; Christian Drosten; Volker Thiel; Edward Trybala
Journal:  PLoS Pathog       Date:  2014-05-29       Impact factor: 6.823
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