| Literature DB >> 23549606 |
Dario Braga1, Lucia Maini, Fabrizia Grepioni.
Abstract
The preparation of co-crystals via mechanochemistry combines the quest for clean and green processes with the investigation of multicomponent new materials, among the currently most fashionable systems in the crystal engineering field: the physico-chemical properties of the components add, merge or transform when co-crystals are formed, giving rise to potentially improved performance in "old" solid-state chemistry fields, as in the pharmaceutical industry field, where they represent a way to obtain new formulations and to improve the properties (solubility, thermal stability, compressibility, etc.) of both new and existing drugs.Year: 2013 PMID: 23549606 DOI: 10.1039/c3cs60014a
Source DB: PubMed Journal: Chem Soc Rev ISSN: 0306-0012 Impact factor: 54.564