Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A (selective) history of Australian involvement in cytokine biology.

Literature DB >> 23548178

A (selective) history of Australian involvement in cytokine biology.

Abstract

This review focuses on contributions to cytokine biology made by Australians in Australia. It is clearly biased by my own experiences and selective recollections especially related to the colony-stimulating factors in which Australian involvement has been pre-eminent from discovery to clinical use. Nevertheless Australian scientists have also made profound contributions to other areas of cytokine and growth factor biology (including interferons, inflammatory cytokines, chemokines and epidermal, insulin-like and vascular endothelial growth factors) that are briefly described in this review as well as other chapters in this volume.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: Australia; Colony-stimulating factors; Cytokine receptors; Cytokines; Signalling

Mesh：

Substances：

Year: 2013 PMID： 23548178 PMCID： PMC3713160 DOI： 10.1016/j.cytogfr.2013.03.004

Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN： 1359-6101 Impact factor: 7.638

Keyword Cloud
References

130 in total

1. The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.

Authors: J G Zhang; A Farley; S E Nicholson; T A Willson; L M Zugaro; R J Simpson; R L Moritz; D Cary; R Richardson; G Hausmann; B T Kile; B J Kile; S B Kent; W S Alexander; D Metcalf; D J Hilton; N A Nicola; M Baca
Journal: Proc Natl Acad Sci U S A Date: 1999-03-02 Impact factor: 11.205

2. Twenty proteins containing a C-terminal SOCS box form five structural classes.

Authors: D J Hilton; R T Richardson; W S Alexander; E M Viney; T A Willson; N S Sprigg; R Starr; S E Nicholson; D Metcalf; N A Nicola
Journal: Proc Natl Acad Sci U S A Date: 1998-01-06 Impact factor: 11.205

3. A family of cytokine-inducible inhibitors of signalling.

Authors: R Starr; T A Willson; E M Viney; L J Murray; J R Rayner; B J Jenkins; T J Gonda; W S Alexander; D Metcalf; N A Nicola; D J Hilton
Journal: Nature Date: 1997-06-26 Impact factor: 49.962

4. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).

Authors: M G Achen; M Jeltsch; E Kukk; T Mäkinen; A Vitali; A F Wilks; K Alitalo; S A Stacker
Journal: Proc Natl Acad Sci U S A Date: 1998-01-20 Impact factor: 11.205

5. Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulating factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors.

Authors: Q Sun; K Jones; B McClure; B Cambareri; B Zacharakis; P O Iversen; F Stomski; J M Woodcock; C J Bagley; R D'Andrea; A F Lopez
Journal: Blood Date: 1999-09-15 Impact factor: 22.113

6. Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.

Authors: S E Nicholson; T A Willson; A Farley; R Starr; J G Zhang; M Baca; W S Alexander; D Metcalf; D J Hilton; N A Nicola
Journal: EMBO J Date: 1999-01-15 Impact factor: 11.598

A (selective) history of Australian involvement in cytokine biology.

1. The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.

2. Twenty proteins containing a C-terminal SOCS box form five structural classes.

3. A family of cytokine-inducible inhibitors of signalling.

4. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).

5. Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulating factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors.

6. Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.

7. Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor.

8. Binding of 125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cells.

9. Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice.

10. Specific binding of radioiodinated granulocyte-macrophage colony-stimulating factor to hemopoietic cells.