Literature DB >> 23547147

Octodon degus (Molina 1782): a model in comparative biology and biomedicine.

Alvaro O Ardiles1, John Ewer, Monica L Acosta, Alfredo Kirkwood, Agustin D Martinez, Luis A Ebensperger, Francisco Bozinovic, Theresa M Lee, Adrian G Palacios.   

Abstract

One major goal of integrative and comparative biology is to understand and explain the interaction between the performance and behavior of animals in their natural environment. The Caviomorph, Octodon degu, is a native rodent species from Chile, and represents a unique model to study physiological and behavioral traits, including cognitive and sensory abilities. Degus live in colonies and have a well-structured social organization, with a mostly diurnal-crepuscular circadian activity pattern. More notable is the fact that in captivity, they reproduce and live between 5 and 7 yr and show hallmarks of neurodegenerative diseases (including Alzheimer's disease), diabetes, and cancer.

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Mesh：

Year:  2013        PMID： 23547147      PMCID： PMC4386868          DOI： 10.1101/pdb.emo071357

Source DB:  PubMed          Journal:  Cold Spring Harb Protoc        ISSN： 1559-6095


  41 in total

1.  Cytomegalic virus-associated insulitis in diabetic Octodon degus.

Authors:  J G Fox; J C Murphy
Journal:  Vet Pathol       Date:  1979-09       Impact factor: 2.221

2.  Retinal photoreceptors of two subterranean tuco-tuco species (Rodentia, Ctenomys): morphology, topography, and spectral sensitivity.

Authors:  Cristian E Schleich; Alex Vielma; Martin Glösmann; Adrian G Palacios; Leo Peichl
Journal:  J Comp Neurol       Date:  2010-10-01       Impact factor: 3.215

Review 3.  Recent rodent models for Alzheimer's disease: clinical implications and basic research.

Authors:  Nady Braidy; Pablo Muñoz; Adrian G Palacios; Gloria Castellano-Gonzalez; Nibaldo C Inestrosa; Roger S Chung; Perminder Sachdev; Gilles J Guillemin
Journal:  J Neural Transm (Vienna)       Date:  2011-11-16       Impact factor: 3.575

4.  Retinal spectral sensitivity, fur coloration, and urine reflectance in the genus octodon (rodentia): implications for visual ecology.

Authors:  Andrés E Chávez; Francisco Bozinovic; Leo Peichl; Adrián G Palacios
Journal:  Invest Ophthalmol Vis Sci       Date:  2003-05       Impact factor: 4.799

5.  Burrow limitations and group living in the communally rearing rodent, Octodon degus.

Authors:  Luis A Ebensperger; Adrian S Chesh; Rodrigo A Castro; Liliana Ortiz Tolhuysen; Verónica Quirici; Joseph Robert Burger; Raúl Sobrero; Loren D Hayes
Journal:  J Mammal       Date:  2011       Impact factor: 2.416

6.  Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu.

Authors:  Nibaldo C Inestrosa; Ariel E Reyes; Marcelo A Chacón; Waldo Cerpa; Aldo Villalón; Juan Montiel; Genevieve Merabachvili; Rebeca Aldunate; Francisco Bozinovic; Francisco Aboitiz
Journal:  Neurobiol Aging       Date:  2004-12-10       Impact factor: 4.673

7.  Seasonal acclimatization in water flux rate, urine osmolality and kidney water channels in free-living degus: molecular mechanisms, physiological processes and ecological implications.

Authors:  Francisco Bozinovic; Pedro A Gallardo; G Henk Visser; Arturo Cortés
Journal:  J Exp Biol       Date:  2003-09       Impact factor: 3.312

8.  Diabetic cataracts and flavonoids.

Authors:  S D Varma; A Mizuno; J H Kinoshita
Journal:  Science       Date:  1977-01-14       Impact factor: 47.728

9.  Gas chromatographic/mass spectrometric evidence for the identification of a heptitol and an octitol in human and Octodon degu eye lenses.

Authors:  S A Barker; F P Fish; M Tomana; L C Garner; R L Settine; J Prchal
Journal:  Biochem Biophys Res Commun       Date:  1983-11-15       Impact factor: 3.575

10.  Basal metabolism is correlated with habitat productivity among populations of degus (Octodon degus).

Authors:  Francisco Bozinovic; José M Rojas; Bernardo R Broitman; Rodrigo A Vásquez
Journal:  Comp Biochem Physiol A Mol Integr Physiol       Date:  2009-01-07       Impact factor: 2.320
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  11 in total

1.  Neural Circuits Underlying Rodent Sociality: A Comparative Approach.

Authors:  Nicole S Lee; Annaliese K Beery
Journal:  Curr Top Behav Neurosci       Date:  2019

2.  Thymoma originating from the cervical component of the thymus in a degu.

Authors:  Naka Okumura; Hirotaka Kondo; Shinichi Suzuki; Hisashi Shibuya
Journal:  J Vet Diagn Invest       Date:  2021-09-13       Impact factor: 1.569

3.  Retinal aging in the diurnal Chilean rodent (Octodon degus): histological, ultrastructural and neurochemical alterations of the vertical information processing pathway.

Authors:  Krisztina Szabadfi; Cristina Estrada; Emiliano Fernandez-Villalba; Ernesto Tarragon; Gyorgy Setalo; Virginia Izura; Dora Reglodi; Andrea Tamas; Robert Gabriel; Maria Trinidad Herrero
Journal:  Front Cell Neurosci       Date:  2015-04-21       Impact factor: 5.505

Review 4.  Genetic variants associated with neurodegenerative Alzheimer disease in natural models.

Authors:  Claudia Salazar; Gonzalo Valdivia; Álvaro O Ardiles; John Ewer; Adrián G Palacios
Journal:  Biol Res       Date:  2016-02-26       Impact factor: 5.612

Review 5.  On cognitive ecology and the environmental factors that promote Alzheimer disease: lessons from Octodon degus (Rodentia: Octodontidae).

Authors:  Daniela S Rivera; Nibaldo C Inestrosa; Francisco Bozinovic
Journal:  Biol Res       Date:  2016-02-20       Impact factor: 5.612

6.  Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent.

Authors:  Maria Angeles Bonmati-Carrion; Beatriz Baño-Otalora; Juan Antonio Madrid; Maria Angeles Rol
Journal:  Sci Rep       Date:  2017-08-18       Impact factor: 4.379

7.  Alzheimer's Disease-Related Protein Expression in the Retina of Octodon degus.

Authors:  Lucia Y Du; Lily Y-L Chang; Alvaro O Ardiles; Cheril Tapia-Rojas; Joaquin Araya; Nibaldo C Inestrosa; Adrian G Palacios; Monica L Acosta
Journal:  PLoS One       Date:  2015-08-12       Impact factor: 3.240

8.  Role of connexin channels in the retinal light response of a diurnal rodent.

Authors:  Angelina Palacios-Muñoz; Maria J Escobar; Alex Vielma; Joaquín Araya; Aland Astudillo; Gonzalo Valdivia; Isaac E García; José Hurtado; Oliver Schmachtenberg; Agustín D Martínez; Adrian G Palacios
Journal:  Front Cell Neurosci       Date:  2014-08-25       Impact factor: 5.505

9.  Revisiting rodent models: Octodon degus as Alzheimer's disease model?

Authors:  Johannes Steffen; Markus Krohn; Kristin Paarmann; Christina Schwitlick; Thomas Brüning; Rita Marreiros; Andreas Müller-Schiffmann; Carsten Korth; Katharina Braun; Jens Pahnke
Journal:  Acta Neuropathol Commun       Date:  2016-08-26       Impact factor: 7.801

10.  Melatonin alleviates circadian system disruption induced by chronic shifts of the light-dark cycle in Octodon degus.

Authors:  Beatriz Bano-Otalora; Juan Antonio Madrid; Maria Angeles Rol
Journal:  J Pineal Res       Date:  2019-11-18       Impact factor: 13.007
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