Literature DB >> 23544807

Therapeutic procedures and use of alternating antipyretic drugs for fever management in children.

Gracian Li Pereira1, Noemia U L Tavares, Sotero S Mengue, Tatiane da S Dal Pizzol.   

Abstract

OBJECTIVE: The evidence on the effectiveness of alternating antipyretics in fever management is scarce and indicates clinically negligible differences. The present study aimed to describe therapeutic procedures and the use of alternating antipyretics in children, and to evaluate associated factors.
METHODS: This was a cross-sectional study with 692 children aged 0 to 6 years, living in Southern Brazil. Household interviews of the children's caregivers were conducted through cluster sampling using a structured questionnaire. A descriptive analysis was carried out, and the association between the use of alternating antipyretics and sociodemographic factors was evaluated. A total of 630 cases were analyzed (91.0%), corresponding to children with a history of fever.
RESULTS: Approximately 73% of caregivers reported that the first measure adopted during the last fever episode was the administration of medication. The mean temperature considered as fever by caregivers was 37.4°C, and as high fever, 38.7°C. The use of alternating antipyretic therapy was reported by 26.7% of respondents, justified by the lack of response to monotherapy and medical indication, in most cases. The drugs most often used were dipyrone and paracetamol. Children whose primary caregiver was a parent with higher socioeconomic status and higher educational level received more alternating medications. Approximately 70% of the doses used were below the minimum recommended dose for the treatment of fever.
CONCLUSIONS: The use of medication to control fever is a common practice, including alternating antipyretic regimens. Most caregivers consider as fever temperatures lower than those established and they reported lack of response to monotherapy and medical indication as the main reasons for alternating medication.
Copyright © 2013 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

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Year:  2013        PMID: 23544807     DOI: 10.1016/j.jped.2013.02.005

Source DB:  PubMed          Journal:  J Pediatr (Rio J)        ISSN: 0021-7557            Impact factor:   2.197


  6 in total

1.  Alternating Acetaminophen and Ibuprofen versus Monotherapies in Improvements of Distress and Reducing Refractory Fever in Febrile Children: A Randomized Controlled Trial.

Authors:  Shuanghong Luo; Mengdong Ran; Qiuhong Luo; Min Shu; Qin Guo; Yu Zhu; Xiaoping Xie; Chongfan Zhang; Chaomin Wan
Journal:  Paediatr Drugs       Date:  2017-10       Impact factor: 3.022

2.  USE OF DRUGS IN CHILDREN AGED ZERO TO FIVE YEARS OLD IN TUBARÃO, SANTA CATARINA, BRAZIL.

Authors:  Hellen Karoline Maniero; Alexandre Alvares Martins; Angelita Cristine Melo; Leonardo Petrus da Silva Paz; Rosiane de Bona Schraiber; Dayani Galato
Journal:  Rev Paul Pediatr       Date:  2018-11-14

3.  [Analysis of parental knowledge and care in childhood fever].

Authors:  Maria-Cristina Pérez-Conesa; Inés Sánchez Pina; Saida Ridao Manonellas; Antoni Tormo Esparza; Verónica García Hernando; Marta López Fernández
Journal:  Aten Primaria       Date:  2017-03-11       Impact factor: 1.137

4.  Over-the-counter antipyretics use among children from Southeastern Poland.

Authors:  Olga Pyznar; Nina Mól; Magdalena Zasada; Wojciech Zasada; Małgorzata Mazurek; Przemko Kwinta
Journal:  J Mother Child       Date:  2021-10-11

Review 5.  A practical approach to the treatment of low-risk childhood fever.

Authors:  Dipak Kanabar
Journal:  Drugs R D       Date:  2014-06

Review 6.  Guidelines for the symptomatic management of fever in children: systematic review of the literature and quality appraisal with AGREE II.

Authors:  Elena Chiappini; Barbara Bortone; Luisa Galli; Maurizio de Martino
Journal:  BMJ Open       Date:  2017-07-31       Impact factor: 2.692

  6 in total

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