| Literature DB >> 23544468 |
Pankaj B Miniyar1, Prashant R Murumkar, Pallavi S Patil, Mahesh A Barmade, Kailash G Bothara.
Abstract
Pyrazine is one of the important class of heterocyclic compounds that can be obtained naturally or synthesized chemically. Pyrazine ring has got importance in exhibiting various biological activities in association with other scaffolds like pyrrole, pyrazole, imidazole, triazole, tetrazole, thiophene, oxazole, pyridine, piperidine and piperazine. Presence of pyrazine ring as a basic scaffold in various clinically used drugs exhibits its importance in drug design. In this review, attempt has been made to disclose various therapeutic applications of pyrazine derivatives reported during the last decade.Entities:
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Year: 2013 PMID： 23544468 DOI： 10.2174/1389557511313110007
Source DB: PubMed Journal: Mini Rev Med Chem ISSN： 1389-5575 Impact factor: 3.862