| Literature DB >> 23543851 |
Alicia Prieto-Langarica1, Hristo Kojouharov, Benito Chen-Charpentier, Liping Tang.
Abstract
S. epidermidis infections on medically implanted devices are a common problem in modern medicine due to the abundance of the bacteria. Once inside the body, S. epidermidis gather in communities called biofilms and can become extremely hard to eradicate, causing the patient serious complications. We simulate the complex S. epidermidis-Neutrophils interactions in order to determine the optimum conditions for the immune system to be able to contain the infection and avoid implant rejection. Our cellular automata model can also be used as a tool for determining the optimal amount of antibiotics for combating biofilm formation on medical implants.Entities:
Keywords: Cellular automata; Medical implants; Neutrophils; S. Epidermidis; biofilms
Year: 2011 PMID: 23543851 PMCID: PMC3611882
Source DB: PubMed Journal: Appl Appl Math ISSN: 1932-9466