Literature DB >> 2354367

Epidermal growth factor receptor expression in demented and aged human brain.

S D Styren1, E J Mufson, G C Styren, W H Civin, J Rogers.   

Abstract

Immunoreactivity to epidermal growth factor receptor (EGFR) was present in the brain vasculature of 13/13 demented elderly patients, but absent in 9/11 non-demented elderly patients. Of the two positive non-demented patients, one had significant Alzheimer's pathology and the other spinal carcinoma. Ultrastructurally, EGFR is localized to the lumenal surface of endothelial cells.

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Year:  1990        PMID： 2354367     DOI： 10.1016/0006-8993(90)90647-t

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  4 in total

1.  Expression of suppressor of cytokine signaling genes in human elderly and Alzheimer's disease brains and human microglia.

Authors:  D G Walker; A M Whetzel; L-F Lue
Journal:  Neuroscience       Date:  2014-10-05       Impact factor: 3.590

Review 2.  Changes in protein kinases in brain aging and Alzheimer's disease. Implications for drug therapy.

Authors:  L W Jin; T Saitoh
Journal:  Drugs Aging       Date:  1995-02       Impact factor: 3.923

3.  Central role of the EGF receptor in neurometabolic aging.

Authors:  Sana Siddiqui; Meng Fang; Bin Ni; Daoyuan Lu; Bronwen Martin; Stuart Maudsley
Journal:  Int J Endocrinol       Date:  2012-06-17       Impact factor: 3.257

4.  Validating a Genomic Convergence and Network Analysis Approach Using Association Analysis of Identified Candidate Genes in Alzheimer's Disease.

Authors:  Puneet Talwar; Suman Kushwaha; Chitra Rawat; Harpreet Kaur; Ankit Srivastava; Rachna Agarwal; Puneet Chandna; Paolo Tucci; Luciano Saso; Ritushree Kukreti
Journal:  Front Genet       Date:  2021-12-09       Impact factor: 4.599
  4 in total

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