AIM: To evaluate the prevalence of coexisting anal human papillomavirus (HPV) infection and concordance of HPV types in women with cervical HPV infection and to investigate the possible predictors for anal HPV infection. METHODS: Study group was composed of women referred with documented cervical HPV infection. All patients had undergone anal HPV DNA testing. RESULTS: One hundred and six patients presenting with cervical HPV infection were eligible for the study. Overall, 24 and 20 distinct HPV genotypes were detected from cervical and anal specimens, respectively. We observed a considerably high prevalence (51.9 %) of coexisting anal HPV infection in our study group. A majority of the women who were found to have anal HPV infection were infected with oncogenic or probable oncogenic types (64.6 %). There were 20.0 and 58.3 % rate of total and partial concordance between the two sites, respectively. We found that no demographic parameter but history of anal intercourse was related with the risk of anal HPV infection. CONCLUSION(S): Women with cervical HPV infection have a considerable risk for coexisting anal HPV infection. Concordance of HPV types infecting the cervix and anal canal is relatively high. There is no strong predictor for anal HPV infection in this population.
AIM: To evaluate the prevalence of coexisting anal human papillomavirus (HPV) infection and concordance of HPV types in women with cervical HPV infection and to investigate the possible predictors for anal HPV infection. METHODS: Study group was composed of women referred with documented cervical HPV infection. All patients had undergone anal HPV DNA testing. RESULTS: One hundred and six patients presenting with cervical HPV infection were eligible for the study. Overall, 24 and 20 distinct HPV genotypes were detected from cervical and anal specimens, respectively. We observed a considerably high prevalence (51.9 %) of coexisting anal HPV infection in our study group. A majority of the women who were found to have anal HPV infection were infected with oncogenic or probable oncogenic types (64.6 %). There were 20.0 and 58.3 % rate of total and partial concordance between the two sites, respectively. We found that no demographic parameter but history of anal intercourse was related with the risk of anal HPV infection. CONCLUSION(S): Women with cervical HPV infection have a considerable risk for coexisting anal HPV infection. Concordance of HPV types infecting the cervix and anal canal is relatively high. There is no strong predictor for anal HPV infection in this population.
Authors: Shitaldas J Pamnani; Alan G Nyitray; Martha Abrahamsen; Dana E Rollison; Luisa L Villa; Eduardo Lazcano-Ponce; Yangxin Huang; Amy Borenstein; Anna R Giuliano Journal: J Infect Dis Date: 2016-08-03 Impact factor: 5.226
Authors: Carlos A R Veo; Sarhan S Saad; José Humberto T G Fregnani; Cristovam Scapulatempo-Neto; Audrey Tieko Tsunoda; Júlio César Possati Resende; Adriana Tarlá Lorenzi; Allini Mafra; Claudia Cinti; Ismael Dale Cotrim; Luciana Albina Reis Rosa; Cristina Mendes de Oliveira; Toni Ricardo Martins; Cristiane Centrone; José Eduardo Levi; Adhemar Longatto-Filho Journal: Tumour Biol Date: 2015-02-13
Authors: Brittney L Dickey; Wenyi Fan; Deepti Bettampadi; Richard R Reich; Bradley Sirak; Martha Abrahamsen; Maria Luiza Baggio; Lenice Galan; Roberto Carvalho Silva; Jorge Salmerón; Luisa L Villa; Eduardo Lazcano-Ponce; Anna R Giuliano Journal: Int J Cancer Date: 2021-07-14 Impact factor: 7.316