Literature DB >> 23543155

Farnesyl and geranylgeranyl transferase inhibitors: an anti-inflammatory effect. Comment to "Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells" Haematologica. 2013;98(1):31-40.

Giulio Kleiner, Annalisa Marcuzzi, Giuseppina Campisciano, Sergio Crovella.   

Abstract

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Year:  2013        PMID: 23543155      PMCID: PMC3660002          DOI: 10.3324/haematol.2012.082040

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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  10 in total

1.  Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia.

Authors:  Judith E Karp; Tatiana I Vener; Mitch Raponi; Ellen K Ritchie; B Douglas Smith; Steven D Gore; Lawrence E Morris; Eric J Feldman; Jacqueline M Greer; Sami Malek; Hetty E Carraway; Valerie Ironside; Steven Galkin; Mark J Levis; Michael A McDevitt; Gail R Roboz; Christopher D Gocke; Carlo Derecho; John Palma; Yixin Wang; Scott H Kaufmann; John J Wright; Elizabeth Garret-Mayer
Journal:  Blood       Date:  2011-10-14       Impact factor: 22.113

2.  Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells.

Authors:  Anne-Kathrin Hechinger; Kristina Maas; Christoph Dürr; Franziska Leonhardt; Gabriele Prinz; Reinhard Marks; Ulrike Gerlach; Maike Hofmann; Paul Fisch; Jürgen Finke; Hanspeter Pircher; Robert Zeiser
Journal:  Haematologica       Date:  2012-07-16       Impact factor: 9.941

3.  Manumycin A, inhibitor of ras farnesyltransferase, inhibits proliferation and migration of rat vascular smooth muscle cells.

Authors:  H Kouchi; K Nakamura; K Fushimi; M Sakaguchi; M Miyazaki; T Ohe; M Namba
Journal:  Biochem Biophys Res Commun       Date:  1999-11-02       Impact factor: 3.575

4.  Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.

Authors:  Joost Frenkel; Ger T Rijkers; Saskia H L Mandey; Sandra W M Buurman; Sander M Houten; Ronald J A Wanders; Hans R Waterham; Wietse Kuis
Journal:  Arthritis Rheum       Date:  2002-10

5.  Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches.

Authors:  Luigina De Leo; Annalisa Marcuzzi; Giuliana Decorti; Alberto Tommasini; Sergio Crovella; Alessandra Pontillo
Journal:  Pharmacol Res       Date:  2010-03-03       Impact factor: 7.658

6.  Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial.

Authors:  J E Karp; J E Lancet; S H Kaufmann; D W End; J J Wright; K Bol; I Horak; M L Tidwell; J Liesveld; T J Kottke; D Ange; L Buddharaju; I Gojo; W E Highsmith; R T Belly; R J Hohl; M E Rybak; A Thibault; J Rosenblatt
Journal:  Blood       Date:  2001-06-01       Impact factor: 22.113

7.  The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.

Authors:  Annalisa Marcuzzi; Luigina De Leo; Giuliana Decorti; Sergio Crovella; Alberto Tommasini; Alessandra Pontillo
Journal:  Pediatr Res       Date:  2011-07       Impact factor: 3.756

8.  A role for geranylgeranylation in interleukin-1beta secretion.

Authors:  Saskia H L Mandey; Loes M Kuijk; Joost Frenkel; Hans R Waterham
Journal:  Arthritis Rheum       Date:  2006-11

Review 9.  Protein prenylation: molecular mechanisms and functional consequences.

Authors:  F L Zhang; P J Casey
Journal:  Annu Rev Biochem       Date:  1996       Impact factor: 23.643

10.  Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency.

Authors:  Annalisa Marcuzzi; Alessandra Pontillo; Luigina De Leo; Alberto Tommasini; Giuliana Decorti; Tarcisio Not; Alessandro Ventura
Journal:  Pediatr Res       Date:  2008-08       Impact factor: 3.756

  10 in total

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