Literature DB >> 23542846

Prospective, before-after cohort study to assess the efficacy of laser therapy on hypertrophic burn scars.

Charles Scott Hultman1, Renee E Edkins, Cindy Wu, Catherine T Calvert, Bruce A Cairns.   

Abstract

INTRODUCTION: Hypertrophic burn scars produce significant morbidity, including itching, pain, stiffness, and contracture. Best practices for management continue to evolve. Lasers have recently been added to treatment algorithms, but indications and efficacy have not been fully defined. We studied the impact of laser therapies on hypertrophic burn scars.
METHODS: We conducted a prospective, before-after study in burn patients with hypertrophic scars. Procedures were performed more than 6 months after burn injury and were repeated monthly. The pulsed-dye laser was used for pruritus and erythema, whereas the fractional CO2 laser was used for stiffness and abnormal texture. All procedures were performed in the OR, with anesthesia. Outcomes are as follows: (1) Vancouver Scar Scale (objective changes in pigmentation, erythema, pliability, height; range, 0-15) and (2) UNC Scar Scale (subjective changes in pain, itching, tingling, stiffness; range, 0-12). Before-after scores were compared by Student t test, with significance assigned to P values of <0.05.
RESULTS: During 2011, we treated 147 patients (mean age, 26.9 years; mean TBSA, 16.1%) over 415 sessions (2.8 sessions/patient), including pulsed dye laser (n = 327) and CO2 (n = 139), mean surface area of 83 cm. Etiology included flame (75), scald (37), and other (35). Treatments occurred 16 months (median) and 48 months (mean) after burn injury. Vancouver Scar Scale decreased from 10.4 (SD, 2.4) to 5.2 (1.9) (P < 0.0001). UNC Scar Scale decreased from 5.4 (2.5) to 2.1 (1.7) (P < 0.0001). Mean length of follow-up was 4.7 months.
CONCLUSIONS: Laser therapies significantly improve both the signs and symptoms of hypertrophic burn scars, as measured by objective and subjective instruments.

Entities:  

Mesh:

Year:  2013        PMID: 23542846     DOI: 10.1097/SAP.0b013e31827eac5e

Source DB:  PubMed          Journal:  Ann Plast Surg        ISSN: 0148-7043            Impact factor:   1.539


  12 in total

1.  Combination of medical needling and non-cultured autologous skin cell transplantation (renovacell) for repigmentation of hypopigmented burn scars in children and young people.

Authors:  K H Busch; R Bender; N Walezko; H Aziz; M A Altintas; M C Aust
Journal:  Ann Burns Fire Disasters       Date:  2016-06-30

Review 2.  Up-to-date approach to manage keloids and hypertrophic scars: a useful guide.

Authors:  Anna I Arno; Gerd G Gauglitz; Juan P Barret; Marc G Jeschke
Journal:  Burns       Date:  2014-04-24       Impact factor: 2.744

3.  LIBERTI: A SMART study in plastic surgery.

Authors:  Jonathan C Hibbard; Jonathan S Friedstat; Sonia M Thomas; Renee E Edkins; C Scott Hultman; Michael R Kosorok
Journal:  Clin Trials       Date:  2018-03-25       Impact factor: 2.486

4.  Early Laser for Burn Scars (ELABS): protocol for a multi-centre randomised, controlled trial of both the effectiveness and cost-effectiveness of the treatment of hypertrophic burn scars with Pulsed Dye Laser and standard care compared to standard care alone [version 1; peer review: 2 approved].

Authors:  Mark Brewin; Sharon Docherty; Vanessa Heaslip; Katie Breheny; Jonathon Pleat; Shelley Rhodes; Paul P M van Zuijlen; Mamta Shah
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5.  Low-intensity LED therapy (658 nm) on burn healing: a series of cases.

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Journal:  Lasers Med Sci       Date:  2017-12-04       Impact factor: 3.161

Review 6.  Efficacy of the Neodymium-Doped Yttrium Aluminum Garnet Laser in the Treatment of Keloid and Hypertrophic Scars: A Systematic Review and Meta-analysis.

Authors:  Lingfeng Pan; Haiyan Qin; Caihong Li; Guang Zhang; Liehao Yang; Lianbo Zhang
Journal:  Aesthetic Plast Surg       Date:  2022-01-21       Impact factor: 2.708

Review 7.  Clinical effects of transparent facial pressure masks: A literature review.

Authors:  Sander B Kant; Carlo Colla; Eric van den Kerckhove; Andrzej Piatkowski de Grzymala
Journal:  Prosthet Orthot Int       Date:  2019-03-12       Impact factor: 1.895

8.  Systematic Review on the Content of Outcome Measurement Instruments on Scar Quality.

Authors:  Michelle E Carrière; Kelly A A Kwa; Louise E M de Haas; Anouk Pijpe; Zephanie Tyack; Johannes C F Ket; Paul P M van Zuijlen; Henrica C W de Vet; Lidwine B Mokkink
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-09-30

9.  A new CO2 laser technique for the treatment of pediatric hypertrophic burn scars: An observational study.

Authors:  Tomasz Żądkowski; Paweł Nachulewicz; Maciej Mazgaj; Magdalena Woźniak; Czesław Cielecki; Andrzej Paweł Wieczorek; Iwona Beń-Skowronek
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

10.  Combination of ablative fractional carbon dioxide laser and platelet-rich plasma treatment to improve hypertrophic scars: a retrospective clinical observational study.

Authors:  Zhanzhan Dai; Xiaozhen Lou; Tuo Shen; Yu Sun; Yongqiang Xiao; Xingfeng Zheng; Xuexin Wang; Yu Peng; Yukun Guo; Yibin Guo; Jiannan Wen; He Fang; Bing Ma; Zhaofan Xia
Journal:  Burns Trauma       Date:  2021-07-28
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