| Literature DB >> 23540686 |
Brian J Geiss1, Jeffrey Wilusz.
Abstract
Chen et al. demonstrate a new way by which noncoding RNAs tailor the function of multicomponent complexes. They show that a noncoding RNA interacts with an exoribonuclease, altering its substrate specificity and enzymatic activity by serving as a ribonucleoprotein scaffold and, perhaps, a gate for entry of the RNA substrate.Entities:
Year: 2013 PMID: 23540686 PMCID: PMC3733347 DOI: 10.1016/j.cell.2013.03.005
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582