Literature DB >> 23539879

Obsessive-compulsive symptoms during the postpartum period. A prospective cohort.

Emily S Miller1, Christine Chu, Jacqueline Gollan, Dana R Gossett.   

Abstract

OBJECTIVE: To estimate the prevalence of postpartum obsessive-compulsive disorder (OCD) symptoms and to ascertain risk factors for this condition. STUDY
DESIGN: This is a prospective cohort of postpartum women carried out from June to September 2009. A total of 461 women were recruited after delivery at a tertiary care institution. Demographic, psychiatric, and obstetric information were collected from each participant. Patients were contacted at 2 weeks and at 6 months postpartum and completed screening tests for depression, anxiety, and OCD.
RESULTS: Eleven percent of women screened positive for OCD symptoms at 2 weeks postpartum. At 6 months postpartum almost half of those women had persistent symptoms, and an additional 5.4% had developed new OCD symptoms. Concomitant positive screens for anxiety and depression were predictive factors for the development of OCD symptoms.
CONCLUSION: Prior population-based studies estimate the prevalence of OCD to be approximately 2-3%. We found much higher rates among women in the postpartum period. The postpartum period is a high-risk time for the development of OCD symptoms. When such symptoms develop, they have a high likelihood of persisting for at least 6 months.

Entities:  

Mesh:

Year:  2013        PMID: 23539879      PMCID: PMC5705036     

Source DB:  PubMed          Journal:  J Reprod Med        ISSN: 0024-7758            Impact factor:   0.142


  34 in total

Review 1.  OCD in the perinatal period: is postpartum OCD (ppOCD) a distinct subtype? A review of the literature.

Authors:  Mary McGuinness; Jackie Blissett; Chris Jones
Journal:  Behav Cogn Psychother       Date:  2011-01-05

2.  The PHQ-9: validity of a brief depression severity measure.

Authors:  K Kroenke; R L Spitzer; J B Williams
Journal:  J Gen Intern Med       Date:  2001-09       Impact factor: 5.128

3.  Relapses after discontinuation of drug associated with increased resistance to treatment in obsessive-compulsive disorder.

Authors:  G Maina; U Albert; F Bogetto
Journal:  Int Clin Psychopharmacol       Date:  2001-01       Impact factor: 1.659

4.  Obsessions and compulsions in women with postpartum depression.

Authors:  K L Wisner; K S Peindl; T Gigliotti; B H Hanusa
Journal:  J Clin Psychiatry       Date:  1999-03       Impact factor: 4.384

5.  Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire.

Authors:  R L Spitzer; K Kroenke; J B Williams
Journal:  JAMA       Date:  1999-11-10       Impact factor: 56.272

6.  The obsessive-compulsive spectrum in the perinatal period: a prospective pilot study.

Authors:  Linda H Chaudron; Neha Nirodi
Journal:  Arch Womens Ment Health       Date:  2010-03-10       Impact factor: 3.633

7.  Pre-discharge anxiety among mothers of well newborns: prevalence and correlates.

Authors:  John R Britton
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8.  Neuroendocrine and behavioral responses to mCPP in Obsessive-Compulsive Disorder.

Authors:  S Khanna; J P John; L P Reddy
Journal:  Psychoneuroendocrinology       Date:  2001-02       Impact factor: 4.905

9.  Measurement issues in postpartum depression part 1: anxiety as a feature of postpartum depression.

Authors:  L E Ross; S E Gilbert Evans; E M Sellers; M K Romach
Journal:  Arch Womens Ment Health       Date:  2003-02       Impact factor: 3.633

10.  New mothers' thoughts of harm related to the newborn.

Authors:  Nichole Fairbrother; Sheila R Woody
Journal:  Arch Womens Ment Health       Date:  2008-05-08       Impact factor: 3.633

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  21 in total

1.  Association between obsessive-compulsive disorder and obstetrical and neonatal outcomes in the USA: a population-based cohort study.

Authors:  Khalidha Nasiri; Nicholas Czuzoj-Shulman; Haim Arie Abenhaim
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Review 2.  Psychiatric Emergencies in Pregnancy and Postpartum.

Authors:  Lisette Rodriguez-Cabezas; Crystal Clark
Journal:  Clin Obstet Gynecol       Date:  2018-09       Impact factor: 2.190

3.  Obsessive-compulsive disorder in pregnancy and the postpartum period: course of illness and obstetrical outcome.

Authors:  Samuel J House; Shanti P Tripathi; Bettina T Knight; Natalie Morris; D Jeffrey Newport; Zachary N Stowe
Journal:  Arch Womens Ment Health       Date:  2015-07-16       Impact factor: 3.633

4.  Postpartum Lactation-Mediated Behavioral Outcomes and Drug Responses in a Spontaneous Mouse Model of Obsessive-Compulsive Disorder.

Authors:  Swarup Mitra; McKenzie Mucha; Savanah Owen; Abel Bult-Ito
Journal:  ACS Chem Neurosci       Date:  2017-10-05       Impact factor: 4.418

5.  Are we overlooking obsessive-compulsive disorder during and after pregnancy? Some arguments for a peripartum onset specifier.

Authors:  Verinder Sharma; Dwight Mazmanian
Journal:  Arch Womens Ment Health       Date:  2020-05-26       Impact factor: 3.633

6.  The impact of perinatal depression on the evolution of anxiety and obsessive-compulsive symptoms.

Authors:  Emily S Miller; Denada Hoxha; Katherine L Wisner; Dana R Gossett
Journal:  Arch Womens Ment Health       Date:  2014-10-30       Impact factor: 3.633

Review 7.  Psychiatric consultation to the postpartum mother.

Authors:  Eleanor A Anderson; Deborah R Kim
Journal:  Curr Psychiatry Rep       Date:  2015-04       Impact factor: 5.285

8.  Postpartum anxiety and comorbid depression in a population-based sample of women.

Authors:  Sherry L Farr; Patricia M Dietz; Michael W O'Hara; Kim Burley; Jean Y Ko
Journal:  J Womens Health (Larchmt)       Date:  2013-10-26       Impact factor: 2.681

9.  Anxiety disorders and obsessive compulsive disorder 9 months after perinatal loss.

Authors:  Katherine J Gold; Martha E Boggs; Maria Muzik; Ananda Sen
Journal:  Gen Hosp Psychiatry       Date:  2014-09-22       Impact factor: 3.238

Review 10.  The neurobiology of parenting: A neural circuit perspective.

Authors:  Johannes Kohl; Anita E Autry; Catherine Dulac
Journal:  Bioessays       Date:  2016-12-06       Impact factor: 4.345

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